816455-01-3Relevant academic research and scientific papers
Asymmetric desymmetrization based on an intramolecular haloetherification: A highly effective and recyclable chiral nonracemic auxiliary, 2-exo-methyl-3-endo-phenyl-5-norbornene-2-carboxaldehyde, for meso-1,3- and meso-1,4-diols
Fujioka, Hiromichi,Fujita, Tetsuya,Kotoku, Naoyuki,Ohba, Yusuke,Nagatomi, Yasushi,Hiramatsu, Atsushi,Kita, Yasuyuki
, p. 5386 - 5397 (2004)
A new chiral auxiliary, a 3-endo-phenyl norbornene aldehyde derivative, which is a crystalline, very stable, and easily handled, was developed for the desymmetrization of meso-1,3- and meso-1,4-diols. The key step of the method, an intramolecular bromoeth
