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Z-glycyl-NG-nitro-L-arginine methyl ester (Z-Gly-NO2-Arg-OMe) is a synthetic peptide derivative that serves as a potent and selective inhibitor of nitric oxide synthase (NOS) enzymes. It is commonly used in biological and medical research to study the role of nitric oxide (NO) in various physiological and pathological processes. The compound is designed to mimic the natural substrate L-arginine, which is converted to nitric oxide and L-citrulline by NOS enzymes. By competitively inhibiting the active site of NOS, Z-Gly-NO2-Arg-OMe prevents the production of nitric oxide, allowing researchers to investigate the effects of NO deficiency or excess in cellular and animal models. Z-glycyl-NG-nitro-L-arginine methyl ester is particularly useful in understanding the complex roles of nitric oxide in the cardiovascular, nervous, and immune systems, as well as its involvement in various diseases such as hypertension, inflammation, and cancer.

81666-53-7

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81666-53-7 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 81666-53-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,1,6,6 and 6 respectively; the second part has 2 digits, 5 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 81666-53:
(7*8)+(6*1)+(5*6)+(4*6)+(3*6)+(2*5)+(1*3)=147
147 % 10 = 7
So 81666-53-7 is a valid CAS Registry Number.

81666-53-7Relevant academic research and scientific papers

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