81668-27-1

Basic information

• Product Name: 1-Butyl-4-(4-chloro-benzoyl)-3-ethyl-4,6-diphenyl-3,4-dihydro-1H-pyridin-2-one
• CAS NO: 81668-27-1
• Molecular Weight: 472.027
• Mol File: 81668-27-1.mol

Chemical Properties

• CAS DataBase Reference: 1-Butyl-4-(4-chloro-benzoyl)-3-ethyl-4,6-diphenyl-3,4-dihydro-1H-pyridin-2-one(CAS DataBase Reference)
• NIST Chemistry Reference: 1-Butyl-4-(4-chloro-benzoyl)-3-ethyl-4,6-diphenyl-3,4-dihydro-1H-pyridin-2-one(81668-27-1)
• EPA Substance Registry System: 1-Butyl-4-(4-chloro-benzoyl)-3-ethyl-4,6-diphenyl-3,4-dihydro-1H-pyridin-2-one(81668-27-1)

Safety Data

• Hazardous Substances Data: 81668-27-1(Hazardous Substances Data)

Upstream product

• 21916-52-9 1-n-butyl-4,6-diphenyl-2-pyridone 
• 811-49-4 ethyllithium 
• 122-01-0 4-chloro-benzoyl chloride 

Relevant articles and documents

Heterocycle Stabilized Carbanions. Two Series of Anomalous Products from 1-Alkyl-4,6-diphenyl-2-pyridones

1-Methyl-, 1-ethyl, and 1-n-butyl-4,6-diphenyl-2-pyridones with lithium di-isopropylamide yield normal products with ketone and aldehydes as electrophiles, but dimeric derivatives with acid chlorides, esters, and alkyl halides.The alkylpyridones react with ethyl- and n-butyl-lithium and an electrophile to give products resulting from alkylation at the 3- and reaction with electrophile at the 4-position.Structures are supported by spectra and reaction mechanisms discussed.

Products from metallation and attempted metallation of 1-alkyl-4,6-diphenyl-2-pyridones and subsequent reaction with electrophiles

The title pyridones form products in which either their own carbanion, or an alkylcarbanion, has added to the 3-position, followed by an electrophile to the 4-position.