81685-52-1Relevant academic research and scientific papers
A 'Biogenetic Like' Synthesis of Perloline, 6-(3,4-dimethoxyphenyl)-5-hydroxy-5,6-dihydrobenzonaphthyridin-4(3H)-one
Duong, Thach,Prager, Rolf H.,Were, Stephen T.
, p. 1431 - 1440 (2007/10/02)
9H-Indenopyridine-1(2H),9-dione, prepared by a new efficient route, reacts with 3,4-dimethoxyphenyllithium to form the keto alcohol (7), which rearranges with hydrazoic acid to form 5-(3,4-dimethoxyphenyl)benznaphthyridin-4(3H)-one.The N-oxide photolyses smoothly to yield dehydroperloline as the sole product.
A Convenient Synthesis of N-Aryl-1,2-dihydro-2-oxo-3-pyridinecarboxamides, N-Aryl-N-methyl-1,2-dihydro-2-oxo-3-pyrimidinecarboxamides and Their 1-Methyl (O-Methyl)-Derivatives
Cativiela, C,Fernandez, J.,Melendez, E.
, p. 1093 - 1097 (2007/10/02)
A new and versatile method for the preparation of the isonixine analogous, N-aryl-1,2-dihydro-2-oxo-3-pyridinecarboxamides and N-aryl-N-methyl-1,2-dihydro-2-oxo-3-pyridinecarboxamides is described via the selective chlorination of 2-hydroxynicotinic acid.
