81701-86-2Relevant academic research and scientific papers
Palladium catalyzed Csp2-H activation for direct aryl hydroxylation: The unprecedented role of 1,4-dioxane as a source of hydroxyl radicals
Seth, Kapileswar,Nautiyal, Manesh,Purohit, Priyank,Parikh, Naisargee,Chakraborti, Asit K.
, p. 191 - 194 (2015/01/09)
A novel strategy for direct aryl hydroxylation via Pd-catalysed Csp2-H activation through an unprecedented hydroxyl radical transfer from 1,4-dioxane, used as a solvent, is reported with bio relevant and sterically hindered heterocycles and various acyclic functionalities as versatile directing groups.
Reaction of Haloazoxybenzenes with Sulfuric Acid
Shimao, Ichiro,Fujimori, Ken,Oae, Shigeru
, p. 546 - 550 (2007/10/02)
Treatment of 4,4'-dihaloazoxybenzenes with sulfuric acid afforded 4,4'-dihaloazobenzenes (6) as the major product and 5-halo-2-(p-halophenylazo)phenols, the Wallach rearrangement products as minor products, besides 2-halo-5-(halophenylazo)phenols, 2-halo-4-(p-halophenylazo)phenols, and 4-(p-halophenylazo)phenols as abnormal rearrangement products.The reaction of fluoro compounds gave the azophenols (3a or 5a) in the best yields.However, the ratio of 3a to 5a was found to vary with the concentration of sulfuric acid.Treatment of 4-haloazoxybenzenes with sulfuric acid gave 4-(p-halophenylazo)phenols and 4-haloazobenzenes (13) as major products together with 2-(p-halophenylazo)phenols and 5-halo-2-(phenylazo)phenols as minor products.Yields of reduction products 6 and 13 increased as the halosubstituent became heavier in the following sequence: F -> Cl -> Br -> I.
