81743-92-2 Usage
General Description
1,2-Benzisoselenazol-3(2H)-one, 2-(4-nitrophenyl)- is a chemical compound with the molecular formula C13H8N2O3Se. It is a selenazolone derivative with a 2-(4-nitrophenyl) substituent. 1,2-Benzisoselenazol-3(2H)-one, 2-(4-nitrophenyl)- has been studied for its potential biological and pharmacological properties, including its anti-cancer and anti-inflammatory activities. Its structure and reactivity make it a potential candidate for drug development and medicinal chemistry research. Further studies are needed to understand its full range of biological activities and potential applications in various fields.
Check Digit Verification of cas no
The CAS Registry Mumber 81743-92-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,1,7,4 and 3 respectively; the second part has 2 digits, 9 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 81743-92:
(7*8)+(6*1)+(5*7)+(4*4)+(3*3)+(2*9)+(1*2)=142
142 % 10 = 2
So 81743-92-2 is a valid CAS Registry Number.
InChI:InChI=1/C13H8N2O3Se/c16-13-11-3-1-2-4-12(11)19-14(13)9-5-7-10(8-6-9)15(17)18/h1-8H
81743-92-2Relevant articles and documents
Water-dependent synthesis of biologically active diaryl diselenides
Pacu?a, Agata J.,Obieziurska, Magdalena,?cianowski, Jacek,Kaczor, Katarzyna B.,Antosiewicz, J?drzej
, p. 153 - 164 (2018/07/05)
A new one-step method for the synthesis of diaryl diselenides has been developed. The reaction of o-iodobenzamides with dilithium diselenide can be controlled by the presence of water providing a simple and efficient protocol to obtain benzisoselenazolones or diaryl diselenides. A series of N-Aryl ebselen derivatives and the corresponding diselenides was obtained. All synthesized compounds were tested in vitro as antioxidants and cytotoxic agents. N-(2,3,4-Trimethoxyphenyl)benzisoselenazol-3(2H)-one was the best in vitro antioxidant and the corresponding diselenide the most potent cytotoxic agent against prostate cancer cell line DU145, being inactive towards healthy prostate cell line PNT1A. Formula parented.
