81777-35-7

Upstream product

• 920-39-8 isopropylmagnesium bromide 
• 350479-90-2 (S,E)-N-benzylidene-4-methylbenzenesulfinamide 
• 100-47-0 benzonitrile 
• 1517-82-4 (1R,2S,5R,SS)-(-)-menthyl p-toluenesulfinate 
• 866993-20-6 (S)-4-methyl-N-(1-phenylethylidene)benzenesulfinamide 

Downstream Products

• 81777-37-9 N-[(R)-2-methyl-1-phenylpropan-1-yl]-4-methylbenzenesulfonamide 
• 627503-87-1 N-[(S)-2-methyl-1-phenylpropan-1-yl]-4-methylbenzenesulfonamide 
• 6668-27-5 (R)-2-methyl-1-phenylpropylamine 
• 6668-27-5 (S)-2-methyl-1-phenylpropane-1-amine 
• 64396-66-3 methyl (R)-4-methylbenzenesulfinate 

Relevant academic research and scientific papers

Stereoselective addition to chiral p-toluene sulfinimines

Diastereoselective addition of a number of Grignard reagents to chiral p-toluene sulfinimines 2b-2d under the mediation of copper salts afforded various protected α-branched amines. (C) 2000 Elsevier Science Ltd.

Asymmetric Induction in the Reduction of Optically Active N-Alkylidenesulphinamides by Metal Hydrides. A New, Efficient Enantioselective Route to Chiral Amines

A series of racemic and optically active N-alkylidenesulphinamides has been prepared and their reduction by metal hydrides studied.The extent of asymmetric synthesis mainly depends on the nature of the reducing species; the best results (up to 92percent of stereoselectivity) are obtained with alkoxy-lithium aluminium hydrides.A new, highly enantioselective synthesis of amines is described.