81805-97-2

Usage

InChI:InChI=1/C10H11BrO3/c1-3-14-9-5-7(6-12)4-8(11)10(9)13-2/h4-6H,3H2,1-2H3

Upstream product

• 1131-52-8 3-ethoxy-4-methoxybenzaldehyde 
• 3111-37-3 3-bromo-5-ethoxy-4-hydroxybenzaldehyde 
• 74-88-4 methyl iodide 

Downstream Products

• 81805-96-1 [1-(3-Bromo-5-ethoxy-4-methoxy-phenyl)-meth-(E)-ylidene]-cyclohexyl-amine 
• 952017-41-3 1-Ethoxy-3-ethylsulfanyl-2-methoxy-5-vinyl-benzene 
• 90132-13-1 3-Ethoxy-4-methoxy-5-methylsulfanyl-benzaldehyde 
• 952017-46-8 1-Ethoxy-3-ethylsulfanyl-5-(2-iodo-ethyl)-2-methoxy-benzene 
• 90132-17-5 3-Ethoxy-5-ethylsulfanyl-4-methoxy-benzaldehyde 
• 90132-25-5 1-Ethoxy-2-methoxy-3-methylsulfanyl-5-((E)-2-nitro-vinyl)-benzene 
• 90132-28-8 1-Ethoxy-3-ethylsulfanyl-2-methoxy-5-((E)-2-nitro-vinyl)-benzene 
• 90132-44-8 2-[2-(3-Ethoxy-5-ethylsulfanyl-4-methoxy-phenyl)-ethyl]-isoindole-1,3-dione 
• 90132-39-1 2-(3-Ethoxy-4-methoxy-5-methylsulfanyl-phenyl)-ethylamine 
• 90132-51-7 2-(3-Ethoxy-5-ethylsulfanyl-4-methoxy-phenyl)-ethylamine 
• 1207549-13-0 C₂₁H₂₃BrN₂O₆ 
• 75287-20-6 3-ethoxy-4,5-dimethoxybenzaldehyde 

Relevant academic research and scientific papers

Solid state nuclear bromination with N-bromosuccinimide. Part 2. Experimental and theoretical studies of reactions with some substituted benzaldehydes

N-Bromosuccinimide reacts with aromatic aldehydes in the solid state to yield exclusively nuclear brominated products while a similar reaction in the solution phase produces a number of products under varied conditions. The reactivity and regioselectivity have been studied in terms of the energies of HOMO, HOMO-LUMO difference, reaction free energy, reaction conditions and crystal packing. Single crystal X-ray structural analysis of 3,4-dihydroxybenzaldehyde has been carried out. Crystal packing energies of some of the reactive and unreactive benzaldehydes indicate the importance of molecular bromine diffusion in the solid state.

Sulfur Analogues of Psychotomimetic Agents. 3. Ethyl Homologues of Mescaline and Their Monothio Analogues

All possible monothio analogues of the mono-, di-, and triethoxy homologues of mescaline have been synthesized and pharmacologically evaluated in man.Modifications at the ring position para to the ethylamine chain, either with a sulfur atom, a longer alkyl chain, or both, lead to compounds of high central nervous system activity.The 4-n-propoxy and 4-n-butoxy homologues and their corresponding 4-thio analogues were also synthesized and pharmacologically evaluated.The propyl homologues retain high potency, but a butyl group (either with or without a sulfur atom) leads to a decrease in activity.The m-ethyl or m-thio analogues retain some central action but the diethoxy and especially the triethoxy homologues are relatively inactive as psychotomimetic drugs.