81829-61-0

Upstream product

• 3132-99-8 m-bromobenzoic aldehyde 
• 126-81-8 dimedone 
• 109-77-3 malononitrile 
• 2972-74-9 2-(3-bromobenzylidene)malononitrile 

Relevant academic research and scientific papers

An eco-friendly innovative halide and metal-free basic ionic liquid catalyzed synthesis of tetrahydrobenzo [b] pyran derivatives in aqueous media: A sustainable protocol

A novel imidazolium-based highly efficient, recoverable, and reusable basic ionic liquid [PEMIM][OH] was synthesized using a very simple approach. This ionic liquid was employed as a catalyst for the multicomponent synthesis of tetrahydrobenzo[b]pyran der

Introduction of succinimide as a green and sustainable organo-catalyst for the synthesis of arylidene malononitrile and tetrahydrobenzo[b] pyran derivatives

Aim and Objective: In this work, we tried to introduce a non-toxic and stable organic compound named succinimide as a green and efficient organo-catalyst for the promotion of the synthesis of arylidene malononitrile and tetrahydrobenzo[b]pyran derivatives

Tungsten oxides: green and sustainable heterogeneous nanocatalysts for the synthesis of bioactive heterocyclic compounds

Tungsten oxide (WO3) as an efficient heterogeneous catalyst was preparedviaa simple hydrothermal route for the synthesis of a wide range of bioactive heterocyclic compounds. The present investigation deals with the rapid and low-cost synthesis

Ionic liquids containing plant derived benzoate as anions, exhibiting supramolecular polymeric aggregation: Impact of the aggregation on organic catalysis in aqueous medium

Naturally occurring benzoic acid (BA) derived anions have been used to prepare halogen free hydrophilic ionic liquids (ILs 1–4). The supramolecular polymeric aggregation behaviour of these ILs has been studied through high-resolution electron spray ioniza

Horsetail plant (Equisetum arvense) and horsetail plant ash: application and comparison of their catalytic activities as novel and natural porous lewis acid catalysts for the one-pot green synthesis of 2-amino-4H-chromene derivatives under solvent-free co

This study aims to use a new medicinal porous plant having a high content of silica known as horsetail and horsetail ash for the first time as novel, efficient, and environmentally friendly natural mild catalysts. The structure of these catalysts was char

Organocatalytic Cascade Knoevenagel–Michael Addition Reactions: Direct Synthesis of Polysubstituted 2-Amino-4H-Chromene Derivatives

Abstract: In this report, we documented novel strategy for the synthesis of bioactive polysubstituted 2-amino-4H-chromine derivatives under a heterogeneous Al-MCM-41-LDH@APTES (ALAM) catalysis. A synthetic procedure is developed to prepare Al-MCM-41-LDH@APTES (ALAM) heterogeneous basic catalysts. Mesoporous Al-MCM-41 is functionalized by known grafting chemistry via layered double hydroxide (LDH) nanosheets and (3-aminopropyl)triethoxysilane (APTES) moiety as a basic organocatalyst. The resulting catalysts contain amino group functionality on the external surface as well as inside the layers and the basicity can be tuned by the loading of APTES. The samples were fully characterized by 29Si and 13C CP/MAS NMR, infrared absorption spectroscopy, TEM, XPS, EDX, TGA, XRD, CO2-TPD, N2 adsorption isotherms measurements, and they were successfully examined for the cascade type Knoevenagel–Michael addition reactions. The product yields associated with these substrates were optimized, and key reaction parameters affecting the yields were identified. The present catalytic method is simple and robust for diversity oriented synthesis which proceeds good to excellent yields without generating any hazards waste. The broad substrate scope, excellent functional group compatibility makes this protocol highly useful towards synthesis of polysubstituted α-cyanoacrylates, α-cyanoacrylonitriles and 2-amino-4H-chromenes with an electron-donating or electron-withdrawing group. We have also successfully established a flow reaction system, gram-scale synthesis as well as catalyst recyclability up to six catalytic cycles without appreciable loss of its activity. Graphic Abstract: [Figure not available: see fulltext.].

Introduction of a new bis-derivative of succinimide (Bis-Su) as a sustainable and efficient basic organo-catalyst for the synthesis of arylidene malononitrile and tetrahydrobenzo[b]pyran derivatives under green conditions

Organo-catalysts have been under great consideration for many years because of their performance and selectivity in the reactions. In this work, a new bis-succinimide (Bis-Su) compound is prepared, identified and used as a green and efficient basic organo

Nickel ferrite (NiFe2O4) nanoparticles as magnetically recyclable nanocatalyst for highly efficient synthesis of 4H-chromene derivatives

An adapted one-pot route to nanocatalyst-assisted synthesis of 4H-chromenes via three component condensation reaction between dimedone, malononitrile, and a broad range of aryl aldehydes by the use of magnetic nickel ferrite nanoparticles is described. By this achievement, not only a novel route to highly efficient synthesis of these series of heterocycles was introduced but also the scope of these medicinally important IP: 127.0.0.1 productsOn: wasFri, developed 10 Jan 2020 via preparation 23:24:53 of some novel products. Above all, a new application Copyright: of nickel ferrite American nanoparticles Scientific(NiFe Publishers 2O4 NPs) as highly efficient, green and magnetically recyclable catalyst has Delivered been introduced. by Ingenta Overall, obtaining good to excellent yields of products, environmentally and economic benign procedure, easy handling, availability of starting materials, use of non-toxic solvents, and high recyclability of nano-catalyst could be countered as most important advantages of this methodology.

Synthesis and antibacterial study of 2-amino-4H-pyrans and pyrans annulated heterocycles catalyzed by sulfated polysaccharide-coated BaFe12O19 nanoparticles

Abstract: In this procedure, the synthesis of ecofriendly, magnetically retrievable BaFe12O19 was reported using a sulfated polysaccharide of?algal origin, Irish moss (IM), as bio-matrix and capping agent. The characterization of BaFe12O19@IM was performed by some physicochemical characterization tools, such?as Fourier transform?infrared spectroscopy, X-ray powder diffraction, scanning electron microscopy, energy-dispersive X-ray spectroscopy, vibrating sample magnetometer, and thermogravimetric analysis. The catalytic performance and recyclability of the introduced heterogeneous catalyst have been explored in the one-pot synthesis of 2-amino-4H-pyrans and pyrans annulated heterocyclic compounds via a three-component reaction between aldehydes, malononitrile, and various C–H activated acidic compound under green reaction conditions. This environmentally benign catalyst displayed high catalytic activity and effective reusability and could maintain its high catalytic efficiency even after six recycling runs. Furthermore, the antibacterial activity of BaFe12O19@IM and the selected compound (4a) toward two types of clinically isolated bacterial strains Escherichia coli (E. coli) and Staphylococcus aureus (S. aureus) was evaluated. The results revealed that BaFe12O19@IM and 2-amino-4-(4-chlorophenyl)-7,7-dimethyl-5-oxo-5,6,7,8-tetrahydro-4H-chromene-3-carbonitrile (4a) showed an effective antibacterial activity against gram-positive S. aureus. Graphic abstract: [Figure not available: see fulltext.].

Synthesis of Eu(III) fabricated spinel ferrite based surface modified hybrid nanocomposite: Study of catalytic activity towards the facile synthesis of tetrahydrobenzo[b]pyrans

The present work demonstrates a modified protocol for thesynthesis of Europium (Eu) anchored iminodiacetic acid functionalized silica modified core-shell CoFe2O4 magnetic nanoparticles.This is the first report of Eu immobilized nanoc