81835-50-9

Basic information

• Product Name: 4-phenyl-2-(pyrrolidin-1-yl)quinoline
• Synonyms: 4-phenyl-2-(pyrrolidin-1-yl)quinoline
• CAS NO: 81835-50-9
• Molecular Weight: 274.365
• Mol File: 81835-50-9.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 4-phenyl-2-(pyrrolidin-1-yl)quinoline(CAS DataBase Reference)
• NIST Chemistry Reference: 4-phenyl-2-(pyrrolidin-1-yl)quinoline(81835-50-9)
• EPA Substance Registry System: 4-phenyl-2-(pyrrolidin-1-yl)quinoline(81835-50-9)

Safety Data

• Hazardous Substances Data: 81835-50-9(Hazardous Substances Data)

Upstream product

• 123-75-1 pyrrolidine 
• 521270-79-1 1-isocyano-2-(2-methoxy-1-phenylethenyl)benzene 
• 104223-75-8 2-Chloro-2-pyrrolidinovinyl-phenyl-keton 
• 10562-42-2 3,3-dichloro-1-phenyl-propenone 
• 521270-76-8 (2-isocyanophenyl)(phenyl)methanone 
• 2835-77-0 (2-aminophenyl)(phenyl)methanone 
• 54567-10-1 N-(2-benzoylphenyl)-formamide 
• 81835-49-6 2-Anilino-2-pyrrolidinovinyl-phenyl-keton 

Relevant articles and documents

A convenient synthesis of quinolines by reactions of o-isocyano-β- methoxystyrenes with nucleophiles

2,4-Disubstituted quinolines have been synthesized by reactions of o-isocyano-β-methoxystyrenes, which can be easily prepared from commercially available o-aminophenyl ketones in three steps, with alkyl(or aryl)lithiums in generally good yields. Subsequently, o-isocyano-β- methoxystyrenes have also proved to react efficiently with lithium dialkylamides to afford the corresponding 4-substituted N,N-dialkylquinolin-2-amines in satisfactory yields. Graphical Abstract.