81838-42-8

Basic information

• Product Name: 2,4-dibenzyl-4H-oxazol-5-one
• Synonyms: 2,4-dibenzyl-4H-oxazol-5-one
• CAS NO: 81838-42-8
• Molecular Weight: 265.312
• Mol File: 81838-42-8.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 2,4-dibenzyl-4H-oxazol-5-one(CAS DataBase Reference)
• NIST Chemistry Reference: 2,4-dibenzyl-4H-oxazol-5-one(81838-42-8)
• EPA Substance Registry System: 2,4-dibenzyl-4H-oxazol-5-one(81838-42-8)

Safety Data

• Hazardous Substances Data: 81838-42-8(Hazardous Substances Data)

Upstream product

• 108-24-7 acetic anhydride 
• 54582-05-7 N-phenylacetyl-3-phenyl-alanine 

Downstream Products

• 54076-39-0 (R)-N²-benzoylphenylalanine 
• 738-75-0 (S)-3-phenyl-2-phenylacetylamino-propionic acid 
• 81837-87-8 N²-<(R)-N²-(phenylacetyl)phenylalanyl>-L-phenylalanine dimethylamide 
• 81838-43-9 N²-<(S)-N²-(phenylacetyl)phenylalanyl>-L-phenylalanine dimethylamide 

Relevant articles and documents

Enantioselective synthesis of dihydrocoumarin derivatives by chiral scandium(iii)-complex catalyzed inverse-electron-demand hetero-Diels-Alder reaction

An asymmetric inverse-electron-demand hetero-Diels-Alder reaction between o-quinone methides and azlactones to generate potentially pharmacological active dihydrocoumarins has been achieved efficiently by using a chiral N,N′-dioxide-Sc(iii) complex as the catalyst. The desired products were obtained in high yields with excellent enantioselectivities and diastereoselectivities (up to 94% yield, 96% ee and >19:1 dr) under mild reaction conditions. A concerted reaction pathway was confirmed by Operando IR and control experiments.