81852-61-1

Upstream product

• 705-95-3 3-cyclohexylacrylic acid methyl ester 

Downstream Products

• 203718-35-8 methyl 2-acetamido-3-[3-(benzoyloxy)-5-(1-bromocyclohexyl)isoxazol-4-yl]-2-(methoxycarbonyl)propanoate 
• 203718-34-7 methyl 2-acetamido-3-[3-(benzoyloxy)-5-cyclohexylisoxazol-4-yl]-2-(methoxycarbonyl)propanoate 
• 203718-30-3 methyl 2-acetamido-3-[2-(acetoxymethyl)-5-cyclohexyl-3-oxoisoxazolin-4-yl]-2-(methoxycarbonyl)propanoate 
• 203718-25-6 methyl 2-acetamido-3-[5-cyclohexyl-2-(methoxymethyl)-3-oxoisoxazolin-4-yl]-2-(methoxycarbonyl)propanoate 
• 203718-33-6 methyl 2-acetamido-3-(5-cyclohexyl-3-hydroxyisoxazol-4-yl)-2-(methoxycarbonyl)propanoate 
• 203718-21-2 4-(bromomethyl)-5-cyclohexyl-2-(methoxymethyl)isoxazolin-3-one 
• 27772-75-4 5-cyclohexyl-3-hydroxyisoxazole 

Relevant academic research and scientific papers

Structure-Activity Relationships in 1,4-Benzodioxan-Related Compounds. 4. Effect of Aryl and Alkyl Substituents at Position 3 on α-Adrenoreceptor Blocking Activity

The observation that the insertion of a phenyl ring at position 3 of WB 4101 (1) afforded a potent and selective α1-adrenoreceptor antagonist, phenodioxan (2), prompted us to further investigate that position of the 2,3-dihydro-1,4-benzodioxin