705-95-3

Usage

Uses

Used in Adhesive Production:
CYCLOHEXANEACRYLIC ACID METHYL ESTER is used as a key component in the formulation of various adhesives for its strong bonding properties and compatibility with a wide range of materials.
Used in Coating Industry:
In the coating industry, CYCLOHEXANEACRYLIC ACID METHYL ESTER is used as a critical ingredient in the development of high-performance coatings that offer excellent adhesion, durability, and resistance to environmental factors.
Used in Polymer Production:
CYCLOHEXANEACRYLIC ACID METHYL ESTER is utilized in the synthesis of polymers to enhance their mechanical properties, such as strength, flexibility, and resistance to wear and tear.
Used in Industrial Settings:
CYCLOHEXANEACRYLIC ACID METHYL ESTER is primarily used in industrial applications, where it is handled by trained professionals who adhere to strict safety protocols to minimize the risks associated with its flammable nature and potential health hazards.

InChI:InChI=1/C10H16O2/c1-12-10(11)8-7-9-5-3-2-4-6-9/h7-9H,2-6H2,1H3/b8-7+

Upstream product

• 15790-87-1 Methyl (E)-2-pentenoate 
• 110-82-7 cyclohexane 
• 20515-15-5 methyl (2E)-4-methylpent-2-enoate 
• 54378-97-1 (E)-4-Methyl-2-hexensaeure-methylester 
• 102617-63-0 (E)-4-Methyl-2-heptensaeure-methylester 
• 24371-94-6 cyclohexylmercury chloride 
• 82101-74-4 methyl (E)-3-(tributylstannyl)acrylate 
• 82101-75-5 (Z)-ethyl 3-(tributylstannyl)acrylate 
• 96-32-2 bromoacetic acid methyl ester 
• 2043-61-0 cyclohexanecarbaldehyde 
• 67-56-1 methanol 
• 695-12-5 vinylcyclohexane 
• 201230-82-2 carbon monoxide 
• 626-62-0 Cyclohexyl iodide 

Downstream Products

• 475056-70-3 (2S,3R)-3-cyclohexyloxirane-2-carbaldehyde 
• 674782-28-6 Aplaviroc 
• 461023-63-2 [3H]-Aplaviroc hydrochloride 
• 676449-46-0 (3R)-1-Butyl-2,5-dioxo-3-[(1R)-1-hydroxy-1-cyclohexylmethyl]-9-benzyl-1,4,9-triazaspiro[5.5]undecane methanesulfonate 
• 80542-17-2 (2R,3S)-2-(t-butoxycarbonylamino)-3-cyclohexyl-3-hydroxypropanoic acid 
• 82655-29-6 (2S,3R)-2-(t-butoxycarbonylamino)-3-cyclohexyl-3-hydroxypropanoic acid 
• 1280013-67-3 (2S,3S)-2-(t-butoxycarbonylamino)-3-cyclohexyl-3-hydroxypropanoic acid 
• 1280013-68-4 C₂₆H₃₉N₃O₃ 
• 1280013-69-5 C₂₆H₃₉N₃O₃ 
• 1280013-70-8 C₂₆H₃₉N₃O₃ 

Relevant academic research and scientific papers

Enantioselective Intermolecular Addition of Aliphatic Amines to Acyclic Dienes with a Pd-PHOX Catalyst

We report a method for the catalytic, enantioselective intermolecular addition of aliphatic amines to acyclic 1,3-dienes. In most cases, reactions proceed efficiently at or below room temperature in the presence of 5 mol % of a Pd catalyst bearing a PHOX ligand, generating allylic amines in up to 97:3 er. The presence of an electron-deficient phosphine within the ligand not only leads to a more active catalyst but also is critical for achieving high site selectivity in the transformation.

Monodisperse amorphous CuB23 alloy short nanotubes: Novel efficient catalysts for Heck coupling of inactivated alkyl halides and alkenes

Heck-type coupling of inactivated alkyl halides and alkenes, catalyzed by amorphous CuB23 alloy short nanotubes, has been developed. Such couplings occur on the surfaces of nanotubes via a single-electron oxidative reaction. The results indicate that CuB23 nanotubes are efficient catalysts to replace Pd and Ni complexes for such Heck-type coupling. This journal is

Palladium-catalyzed alkoxycarbonylation of terminal alkenes to produce α,β-unsaturated esters: The key role of acetonitrile as a ligand

A mild protocol has been developed for the PdII-catalyzed alkoxycarbonylation of terminal olefins to produce α,β-unsaturated esters with a wide range of substrates. Key features are the use of MeCN as solvent (and/or ligand) to control the reactivity of the intermediate Pd complexes and the combination of CO with O2, which facilitates the CuII-mediated reoxidation of the Pd0 complex to Pd II and prevents double carbonylation. Acetonitrile is the key! A mild protocol has been developed for the PdII-catalyzed alkoxycarbonylation of terminal olefins to produce α,β-unsaturated esters with a wide range of substrates (see scheme). Key features are the use of MeCN as a solvent (and/or ligand) to control the reactivity of the intermediate Pd complexes and the combination of CO with O2, which facilitates the CuII-mediated reoxidation of Pd0 to PdII and prevents double carbonylation.

Chiral magnesium(II) binaphtholates as cooperative bronsted/lewis acid-base catalysts for the highly enantioselective addition of phosphorus nucleophiles to α,β-unsaturated esters and ketones

A little cooperation goes a long way: The cooperative Bronsted/Lewis acid-base supramolecular catalysts formed in situ from simple chiral magnesium(II) binaphtholate aqua complexes promoted the highly enantioselective 1,4-hydrophosphinylation of α,β-unsaturated esters with diaryl phosphine oxides and 1,2-hydrophosphonylation of α,β-unsaturated ketones with dialkyl phosphites (see scheme). Copyright

Discovery of 4-[4-({(3R)-1-butyl-3-[(R)-cyclohexyl(hydroxy)methyl]-2,5- dioxo-1,4,9-triazaspiro[5.5]undec-9-yl}methyl)phenoxy]benzoic acid hydrochloride: A highly potent orally available CCR5 selective antagonist

Based on the original spirodiketopiperazine design framework, further optimization of an orally available CCR5 antagonist was undertaken. Structural hybridization of the hydroxylated analog 4 derived from one of the oxidative metabolites and the new orally available non-hydroxylated benzoic acid analog 5 resulted in another potent orally available CCR5 antagonist 6a as a clinical candidate. Full details of a structure-activity relationship (SAR) study and ADME properties are presented.

Spirodiketopiperazine-based CCR5 antagonist: Discovery of an antiretroviral drug candidate

Following the discovery that hydroxylated derivative 3 (Fig. 1) was one of the oxidative metabolites of the original lead 1, it was found that hydroxylated compound 4 possesses higher in vitro anti-HIV potency than the corresponding non-hydroxylated compo

Investigations on the Selectivity of the β-Scission of Alkyl-Radicals, II - Selectivity of the β-Fragmentation of α-(Methoxycarbonyl)alkyl Radicals

The rate of β-scission of α-(methoxycarbonyl)alkyl radicals 3 and 9, generated by addition of cycloalkyl radicals to appropriate methyl 2-methylenealkanoates 1 and methyl (E)-2-alkenoates 8, resp., has been measured relative to the hydrogen transfer from cycloalkanes.The rate of β-scission increases with increasing stability of the leaving radical R*.Polar effects reversing the stability sequence have also been observed, e.g. the more stable (methoxycarbonyl)methyl radical leaves more slowly than a less stable secondary alkyl radical.

GENERATION AND SYNTHETIC USE OF ALKYL RADICALS WITH 2 AS MEDIATOR

Irradiation of dimeric iron complex 1 in the presence of alkyl halides yields alkyl radicals that are useful in organic synthesis.

Electron-transfer processes. 43. Attack of alkyl radicals upon 1-alkenyl and 1-alkynyl derivatives of tin and mercury

Alkyl radicals, obtained by reaction of Bu3Sn? or ClHg? with alkylmercury halides, will undergo regioselective and in some cases stereospecific substitution by a free radical chain addition-elimination mechanism with 1-alkenylstannanes or -mercurials. The chain reaction is also observed for 1-alkynyl derivatives and in the photostimulated demercuration of mixed alkyl and 1-alkenyl- or 1-alkynylmercurials. Chain propagation with alkyl radical formation is also observed to occur in the reactions of β-eliminated ClHg? with Grignard reagents in PhH-THF solution. In competitive reactions of Bu3Sn? or ClHg? with pairs of alkylmercury chlorides, it is observed that a tert-butylmercurial is >1000 times more reactive than a n-butylmercurial, suggesting a concerted dissociate electron-transfer process not involving the intermediacy of RHg? species.