81873-12-3Relevant articles and documents
Reactions of Forskolin, a Biologically Active Diterpenoid from Coleus forskohlii
Bhat, Sujata V.,Bajwa, Balbir S.,Dornauer, Horst,Souza, Noel J. de
, p. 767 - 772 (2007/10/02)
Forskolin (1) (7β-acetoxy-8,13-epoxy-1α,6β,9α-trihydroxylabd-14-en-11-one), the major diterpenoid of Coleus forskohlii, has potent positive inotropic, antihypertensive, and adenylate cyclase stimulant properties.The reactivity of its various functional groups (1α-OH, 6β-OH, the derived 7β-OH, 9α-OH, 11-oxo, and 14,15-double bond) has been studied through acylation, alkylation, dehydration, oxidation, and reduction reactions.