81926-94-5

Usage

Uses

Used in Pharmaceutical Industry:
ETHYLDOCOSAHEXAENOATE is used as a pharmaceutical ingredient for its potential health benefits. It is known to have anti-inflammatory properties and may be used in the development of treatments for various inflammatory conditions.
Used in Cosmetic Industry:
In the cosmetic industry, ETHYLDOCOSAHEXAENOATE is used as an emollient and skin conditioning agent. Its ability to moisturize and nourish the skin makes it a valuable component in skincare products.
Used in Food Industry:
ETHYLDOCOSAHEXAENOATE is used as a food additive for its health-promoting properties. It is a source of omega-3 fatty acids, which are essential for maintaining heart and brain health. It can be incorporated into various food products to enhance their nutritional value.
Used in Research Applications:
In research settings, ETHYLDOCOSAHEXAENOATE is used as a chemical probe to study the biological effects of docosahexaenoic acid and its derivatives. It can help scientists understand the mechanisms by which these compounds exert their health benefits and develop new therapeutic strategies.

Upstream product

• 53046-97-2 (Z,Z)-1-hydroxynona-3,6-diene 
• 6217-54-5 docosahexaenoic acid 
• 64-17-5 ethanol 
• 105-58-8 Diethyl carbonate 
• 122-51-0 orthoformic acid triethyl ester 
• 98776-99-9 (4Z,7Z,10Z,13Z,16Z,19Z)-docosa-4,7,10,13,16,19-hexaenoyl chloride 
• 161794-74-7 (3Z,6Z)-nona-3,6-dienyl p-toluenesulfonate 
• 159145-96-7 Toluene-4-sulfonic acid (3Z,6Z)-8-(2,2-dimethyl-[1,3]dioxolan-4-yl)-octa-3,6-dienyl ester 
• 159145-99-0 Ethyl (Z,Z,Z)-13,14-O-Isopropylidenetetradeca-4,7,10-trienoate 
• 159145-91-2 1-(Tosyloxy)-5-hexen-2-yne 
• 159146-00-6 Ethyl (Z,Z)-13,14-Dihydroxytetradeca-4,7,10-trienoate 
• 159145-92-3 1-(Tetrahydropyranyloxy)dec-9-ene-3,6-diyne 
• 159145-95-6 (Z,Z)-9,10-O-Isopropylidenedeca-3,6-dien-1-ol 
• 159145-94-5 9,10-O-isopropylidenedeca-3,6-diyn-1-ol 

Downstream Products

• 105-54-4 butanoic acid ethyl ester 
• 124596-98-1 triglyceride of docosahexaenoic acid 
• 102783-20-0 (4Z,7Z,10Z,13Z,16Z,19Z)-docosa-4,7,10,13,16,19-hexaen-1-ol 
• 78144-19-1 5-[(3Z,6Z,9Z,12Z,15Z)-1-iodooctadeca-3,6,9,12,15-pentaenyl]dihydro-2(3H)-furanone 
• 845673-68-9 5-[(3Z,6Z,9Z,12Z,15Z)-1-hydroxyoctadeca-3,6,9,12,15-pentaenyl]dihydro-2(3H)-furanone 
• 105517-82-6 (14Z,17Z,20Z,23Z,26Z,29Z)-dotriaconta-14,17,20,23,26,29-hexaenoic acid 
• 98776-99-9 (4Z,7Z,10Z,13Z,16Z,19Z)-docosa-4,7,10,13,16,19-hexaenoyl chloride 
• 2566-90-7 all-cis-4,7,10,13,16,19-docosahexaenoic acid methyl ester 
• 121818-29-9 methyl 3-(3-((2Z,5Z,8Z,11Z,14Z)-heptadeca-2,5,8,11,14-pentaen-1-yl)oxiran-2-yl)propanoate 
• 6217-54-5 docosahexaenoic acid 
• 162758-94-3 N-docosahexaenoylethanolamine 
• 1048012-06-1 (4Z,7Z,10Z,13Z,16Z,19Z)-N-(2,3-dihydroxypropyl)docosa-4,7,10,13,16,19-hexaenamide 
• 140670-40-2 (4Z,7Z,10Z,13Z,16Z,19Z)-Docosa-4,7,10,13,16,19-hexaenoic acid 2,3-dihydroxy-propyl ester 

Relevant academic research and scientific papers

Proline derivatives incorporating hydrophobic long-chain derived from natural and synthetic fatty acids

The α-hydrophobic long chain-α-amino esters are prepared by α-hydroxylation of a series of fatty acid esters [derived from oleic acid (OA), linoleic acid (LA), arachidonic acid (ARA) and docosahexaenoic acid (DHA)] followed by Mitsunobu reaction and hydrazinolysis of the phthalimide. These amino esters are mixed with aldehydes and electrophilic alkenes to give very good chemical yields and diastereoselectivities of prolinate derivatives incorporating a hydrophobic long chain at the α-position. This multicomponent 1,3-dipolar cycloaddition (1,3-DC) takes place at room temperature. The synthesis of the homologue hydrophobic chain of OA is performed by its oxidation to aldehyde/racemic N-tert-butylsulfinyl imine/Neff reaction. Final 1,3-DC with benzaldehyde and N-methylmaleimide affords homologue prolinate derivative in good yield.

Preparation of n-3 PUFAs ethyl esters by an efficient biocatalyzed solvent-free process

alpha-Linolenic acid (ALA), eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) have been subjected to esterification with ethanol in presence of lipase B from Candida antarctica (Novozym 435), in solvent free condition. The use of alcohol donors triethyl orthoformate (TEOF) or diethyl carbonate (DEC) instead of free ethanol, allowed working in irreversible esterification conditions and ALA-, EPA- and DHA-ethyl esters were obtained in quantitative yields.

METHODS OF PREPARING FREE POLYUNSATURATED FATTY ACIDS

Provided herein are methods of making compositions of free fatty acids and alkyl esters of polyunsaturated fatty acids (PUFAs). Also provided are compositions comprising a PUFA selected from a free fatty acid or a ester wherein the PUFA is made according to a method of the invention.

Compositions and methods of omega polyunsaturated fatty acids for the treatment of oral diseases

The invention discloses a novel discovery of anti-microbial activity against oral bacteria, which can be applied for controlling and preventing oral diseases, of omega-3, omega-6, and omega-9 fatty acids, but not limited to omega-3, omega-6, and omega-9 fatty acids; omega-3, omega-6, and omega-9 fatty acid methyl esters, and omega-3, omega-6, omega-9 fatty acid ethyl esters and their application method. The application of this discovery includes the preparation of drugs, dietary supplements, food and daily necessities with oral health care and therapeutic effects.

Process for the preparation of a composition comprising unsaturated compounds

The present invention relates to a process for the preparation of a composition comprising unsaturated compounds, in particular polyunsaturated compounds, which comprises concentrating and purifying the compounds by contact with silicon and/or aluminium derivatives. The process of the invention represents an advantageous substitute of the usual distillation processes, coupled or not to chromatographic processes, and allows to isolate and remove polar byproducts.

New Synthon for the Convergent Construction of Skipped Conjugation Polyenes: Synthesis of Ethyl Docosa-4,7,10,13,16,19-hexaenoate

The preparation and subsequent Wittig reaction of the (Z,Z)-phosphonium salt 4, a useful synthon for the preparation of skipped conjugation polyenes, are reported.Salt 4 is a key intermediate for the synthesis of ethyl docosa-4,7,10,13,16,19-hexaenoate (3