161794-74-7Relevant articles and documents
First total synthesis of pro-resolving and tissue-regenerative resolvin sulfido-conjugates
Rodriguez, Ana R.,Spur, Bernd W.
, p. 1662 - 1668 (2017/04/04)
The first total synthesis of the pro-resolving and tissue-regenerative resolvin sulfido-conjugates: 7S,8R,17S-RCTR1, 7S,8R,17S-RCTR2 and 7S,8R,17S-RCTR3, derived from docosahexaenoic acid, has been achieved. Two synthetic approaches are described. Chiral
Antioxidant behaviour of thia fatty acids
Easton, Christopher J.,Ferrante, Antonio,Robertson, Thomas A.,Xia, Ling
, p. 647 - 653 (2007/10/03)
Eight thia fatty acids and other sulfides have been studied as inhibitors of autoxidation of arachidonic acid. The inhibitors extend the lag phase of the oxidation, to varying degrees. A carboxyl group in the vicinity of the sulfur reduces the antioxidant activity, while unsaturated sulfides are more effective than their saturated analogues. The results are consistent with the sulfides acting to reduce fatty acid hydroperoxides, which otherwise accumulate during the early stages of reaction and propagate the free-radical oxidation process.
