81938-91-2

Upstream product

• 111820-53-2 (S)-2-((3S,7S)-1-tert-Butoxycarbonylmethyl-2-oxo-7-phenyl-azepan-3-ylamino)-4-phenyl-butyric acid ethyl ester 
• 111743-11-4 ((3R,7R)-3-Azido-2-oxo-7-phenyl-azepan-1-yl)-acetic acid tert-butyl ester 
• 111743-14-7 ((3R,7R)-3-Amino-2-oxo-7-phenyl-azepan-1-yl)-acetic acid tert-butyl ester 
• 111743-08-9 rac-(3S,7S)-3-azido-7-phenylazepan-2-one 
• 111742-98-4 6-Amino-6-phenyl-hexanoic acid 2,5-dioxo-pyrrolidin-1-yl ester; hydrochloride 
• 111742-97-3 6-tert-Butoxycarbonylamino-6-phenyl-hexanoic acid 2,5-dioxo-pyrrolidin-1-yl ester 
• 111742-96-2 6-tert-Butoxycarbonylamino-6-phenyl-hexanoic acid 
• 111742-93-9 6-[(E)-Hydroxyimino]-6-phenyl-hexanoic acid ethyl ester 
• 152607-29-9 3-Bromo-7-phenyl-hexahydroazepin-2-one 
• 4248-25-3 ethyl 6-oxo-6-phenylhexanoate 
• 111742-99-5 hexahydro-7-phenyl-1H-azepin-2-one 
• 111820-56-5 (S)-2-((3S,7S)-1-Carboxymethyl-2-oxo-7-phenyl-azepan-3-ylamino)-4-phenyl-butyric acid ethyl ester; hydrochloride 

Relevant academic research and scientific papers

Angiotensin-converting enzyme inhibitors. 2. Perhydroazepin-2-one derivatives

α-[(3S)-3-[[(S)-1-(Ethoxycarbonyl)-3-phenylpropyl]amino]-2-oxo-6 or 7-phenylperhydroazepin-1-yl]acetic acids (monoester monoacids) and their dicarboxylic acids were synthesized, and their angiotensin-converting enzyme (ACE) inhibitory activities were eval