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[6-(4-Bromo-phenyl)-3-(4-chloro-phenyl)-imidazo[2,1-b]thiazol-2-yl]-acetic acid ethyl ester is a complex organic compound with the molecular formula C18H14BrClN2O2S2. It features a core imidazo[2,1-b]thiazole structure, which is fused with a benzene ring at the 4-position and substituted with a bromine atom at the 4-position of the phenyl group. Additionally, it has a chlorine atom at the 4-position of another phenyl group attached at the 3-position. The molecule is further characterized by an acetic acid group at the 2-position, which is esterified with an ethyl group. [6-(4-Bromo-phenyl)-3-(4-chloro-phenyl)-imidazo[2,1-b]thiazol-2-yl]-acetic acid ethyl ester is known for its potential applications in medicinal chemistry, particularly as a precursor in the synthesis of drugs targeting various biological pathways. Its unique structure with halogenated aryl groups and a thiazole ring system may contribute to its interaction with specific protein targets, making it a subject of interest in the development of new therapeutic agents.

81950-21-2

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81950-21-2 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 81950-21-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,1,9,5 and 0 respectively; the second part has 2 digits, 2 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 81950-21:
(7*8)+(6*1)+(5*9)+(4*5)+(3*0)+(2*2)+(1*1)=132
132 % 10 = 2
So 81950-21-2 is a valid CAS Registry Number.

81950-21-2Relevant academic research and scientific papers

Synthesis and Anthiinflammatory Activity of Some Arylimidazothiazolyl- and Arylimidazobenzothiazolyl-acetic Acids

Sawhney, S. N.,Kodali, Dharma R.,Dhindsa, G. S.,Singh, S. P.

, p. 134 - 138 (2007/10/02)

Three series of the title compounds, imidazothiazolyl-, imidazobenzothiazolyl- and imidazobenzothiazolylaryl-acetic acids (II,III and IV) have been synthesised for evaluation as potential anti-inflammatory agents.Compounds II have been synthesised by condensing ethyl (2-amino-4-aryl-5-thiazolyl)acetate (VI) with phenacyl bromides followed by hydrolysis of the resultant esters (VII).III are obtained by the condensatiion of ethyl 2-aminobenzothiazole-6-acetate with phenacyl bromides followed by hydrolysis of the resultant esters (IX).Compound IV result from the treatment of 2-aminobenzothiazoles with ethyl 4(ω-bromoacetylphenyl)acetate (XI) followed by hydrolysis of the esters (XII).Some of the title compounds show good antiinflammatory activity.

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