33002-89-0

Upstream product

• 17356-08-0 thiourea 
• 35158-46-4 3-bromo-4-(4-chloro-phenyl)-4-oxo-butyric acid ethyl ester 

Downstream Products

• 81950-19-8 [3-(4-Chloro-phenyl)-6-phenyl-imidazo[2,1-b]thiazol-2-yl]-acetic acid ethyl ester 
• 81950-20-1 [3,6-Bis-(4-chloro-phenyl)-imidazo[2,1-b]thiazol-2-yl]-acetic acid ethyl ester 
• 81950-21-2 [6-(4-Bromo-phenyl)-3-(4-chloro-phenyl)-imidazo[2,1-b]thiazol-2-yl]-acetic acid ethyl ester 
• 81950-22-3 [3-(4-Chloro-phenyl)-6-(4-methoxy-phenyl)-imidazo[2,1-b]thiazol-2-yl]-acetic acid ethyl ester 
• 49780-06-5 Ethyl [2-(phenylaminocarbonylamino)-4-p-chlorophenyl-thiazol-5-yl]-acetate 
• 49780-05-4 ethyl 2-(2-acetamido-4-(4-chlorophenyl)thiazol-5-yl)acetate 
• 81950-09-6 [6-Biphenyl-4-yl-3-(4-chloro-phenyl)-imidazo[2,1-b]thiazol-2-yl]-acetic acid 
• 81950-08-5 [3-(4-Chloro-phenyl)-6-(4-methoxy-phenyl)-imidazo[2,1-b]thiazol-2-yl]-acetic acid 
• 81950-07-4 [6-(4-Bromo-phenyl)-3-(4-chloro-phenyl)-imidazo[2,1-b]thiazol-2-yl]-acetic acid 
• 81950-06-3 [3,6-Bis-(4-chloro-phenyl)-imidazo[2,1-b]thiazol-2-yl]-acetic acid 
• 81950-05-2 [3-(4-Chloro-phenyl)-6-phenyl-imidazo[2,1-b]thiazol-2-yl]-acetic acid 
• 81950-47-2 [6-Biphenyl-4-yl-3-(4-chloro-phenyl)-imidazo[2,1-b]thiazol-2-yl]-acetic acid ethyl ester 

Relevant academic research and scientific papers

Synthesis and Anthiinflammatory Activity of Some Arylimidazothiazolyl- and Arylimidazobenzothiazolyl-acetic Acids

Three series of the title compounds, imidazothiazolyl-, imidazobenzothiazolyl- and imidazobenzothiazolylaryl-acetic acids (II,III and IV) have been synthesised for evaluation as potential anti-inflammatory agents.Compounds II have been synthesised by condensing ethyl (2-amino-4-aryl-5-thiazolyl)acetate (VI) with phenacyl bromides followed by hydrolysis of the resultant esters (VII).III are obtained by the condensatiion of ethyl 2-aminobenzothiazole-6-acetate with phenacyl bromides followed by hydrolysis of the resultant esters (IX).Compound IV result from the treatment of 2-aminobenzothiazoles with ethyl 4(ω-bromoacetylphenyl)acetate (XI) followed by hydrolysis of the esters (XII).Some of the title compounds show good antiinflammatory activity.