81963-12-4

Upstream product

• 3863-11-4 3,4-difluoroaniline 
• 132142-65-5 7-Bromo-3-ethylthio-4,5-difluoro-2-methylindole 
• 85462-60-8 4,5-Difluoro-2-methylindole 
• 64695-79-0 2-bromo-4,5-difluoro-aniline 
• 121247-19-6 <<(3,4-difluoro-2-(2-hydroxypropyl)phenyl)amino>methylene>propanedioic acid diethyl ester 
• 121247-20-9 <(4,5-difluoro-2,3-dihydro-2-methyl-1H-indol-1-yl)methylene>propanedioic acid diethyl ester 
• 121247-16-3 1-(2,3-difluoro-6-nitrophenyl)propan-2-one 
• 121247-17-4 3,4-difluoro-2-(2-hydroxypropyl)nitrobenzene 
• 121247-18-5 3,4-difluoro-2-(2-hydroxypropyl)aniline 
• 771-69-7 2,3,4-trifluoronitrobenzene 
• 85730-59-2 4,5-difluoro-2-methyl-2,3-dihydro-1H-indole 
• 87-13-8 diethyl 2-ethoxymethylenemalonate 
• 85730-60-5 8,9-difluoro-2-methyl-6-oxo-1,2-dihydropyrrolo<3,2-ij>quinoline-5-carboxylic acid ethyl ester 

Relevant academic research and scientific papers

Pyrroloquinoline derivatives and pharmaceutical compositions for antimicrobial use

There is described pyrroloquinoline derivatives of general formula: STR1 wherein R' is a C1 -C6 alkyl group, R2 is a group: STR2 or group: STR3 wherein R3, R4, R5 and R6 are as d

Synthesis of 8,9-difluoro-2-methyl-6-oxo-1,2-dihydropyrrolo[3,2,1-ij]quinoline-5-c arboxylic acid

A new and efficient seven-step synthesis of 8,9-difluoro-2-methyl-6-oxo-1,2-dihydropyrrolo[3,2,1-ij]-quinoline-5- carboxylic acid (9), an important intermediate used in the synthesis of quinolone antibacterials, has been developed beginning with commercia