81965-08-4Relevant academic research and scientific papers
An efficient microwave-assisted synthesis of dihydropyrazinones and bis-benzoylketones
Hossain, Mamun M.,Islam, Rabiul M.,Saha, Sukanta K.,Islam, Mohammad K.
scheme or table, p. 1155 - 1157 (2010/04/25)
Microwave-assisted modified Sandmeyer reactions of oximinoacetanilides, themselves obtained from substituted primary aromatic amines, in concentrated H2SO4 give isatins. N-Acetylisatins undergo ring cleavage and subsequent ring closing with alkanediamines in the presence of ethanol under MW irradiation to give the corresponding dihydropyrazinones in excellent yields. Modification of the reaction conditions affords bis-benzoylketones under MW irradiation.
Synthesis of 5H-pyrazino[2,3-b]indoles from indole-2,3-dione derivatives
Bergman, Jan,Vallberg, Hans
, p. 742 - 752 (2007/10/03)
Reaction of N-acetylindol-2,3-diones with ethylenediamines gave the dihydropyrazinones 11, which could, after dehydrogenation and deacetylation, be transformed to the corresponding 5H-pyrazino[2,3-e]indoles 5. N,N-Dimethylaminoethylation of the anion of 5
Reaction of N-Acylisatins with Diamines
Joshi, B. S.,Likhate, M. A.,Viswanathan, N.
, p. 114 - 116 (2007/10/02)
The reaction of N-acylisatins with aromatic and heterocyclic 1,2-diamines results in opening of the N-C2 bond and leads to the 2-o-acetamidophenylquinoxaline derivatives (6) and (7).With ethylenediamine and 1,3-diaminopropane, compounds (9a) and (9b) resp
