81969-90-6Relevant articles and documents
A Tin-Mediated One-Step Synthesis of (+)-Dicrotaline, an 11-Membered Dilactonic Pyrrolizidine Alkaloid
Niwa, Haruki,Okamoto, Osamu,Ishiwata, Hiroyuki,Kuroda, Akio,Uosaki, Youichi,Yamada, Kiyoyuki
, p. 3017 - 3019 (1988)
A new synthesis of (+)-dicrotaline (1), an 11-membered dilactonic pyrrolizidine alkaloid of retronecine (6) type has been achieved in one step by utilizing a tin-mediated lactonization process.
Synthesis and Stereochemistry of Dicrotaline, a Macrocyclic Pyrrolizidine Alkaloid
Devlin, J. Alastair,Robins, David J.
, p. 1272 - 1274 (2007/10/02)
Dicrotaline (3) and its C-13 epimer (4) have been synthesized and the absolute configuration at C-13 of both alkaloids has been established by specific degradation of each epimer to optically active mevalonolactone.