81971-39-3

Basic information

• Product Name: 5-BROMO-1-METHYL-2(1H)-PYRIDINONE
• Synonyms: 5-BROMO-1-METHYL-2(1H)-PYRIDINONE;5-BroMo-1-Methyl-1H-pyridin-2-one;5-BroMo-1-Methylpyridin-2...;3-Bromo-1-methyl-6-oxo-1,6-dihydropyridine;5-Bromo-1-methyl-2(1H)-pyridone;5-bromo-1-methyl-1,2-dihydropyridin-2-one;5-Bromo-1-methylpyridin-2(1H)-one;5-Bromo-1-methyl-pyridin-2-one
• CAS NO: 81971-39-3
• Molecular Formula: C₆H₆BrNO
• Molecular Weight: 188.03
• Mol File: 81971-39-3.mol
• Article Data: 2

Chemical Properties

• Melting Point: 62-63℃
• Boiling Point: 258℃
• Flash Point: 110℃
• Appearance: /
• Density: 1.664
• Storage Temp.: Inert atmosphere,Room Temperature
• CAS DataBase Reference: 5-BROMO-1-METHYL-2(1H)-PYRIDINONE(CAS DataBase Reference)
• NIST Chemistry Reference: 5-BROMO-1-METHYL-2(1H)-PYRIDINONE(81971-39-3)
• EPA Substance Registry System: 5-BROMO-1-METHYL-2(1H)-PYRIDINONE(81971-39-3)

Safety Data

• Hazardous Substances Data: 81971-39-3(Hazardous Substances Data)

Usage

General Description

5-BROMO-1-METHYL-2(1H)-PYRIDINONE is a chemical compound with the molecular formula C6H6BrNO. It is a derivative of pyridine and is commonly used as an intermediate in the synthesis of various pharmaceuticals, agrochemicals, and fine chemicals. 5-BROMO-1-METHYL-2(1H)-PYRIDINONE is known for its diverse range of applications, including its use as a building block in organic synthesis, particularly in the production of pesticides and pharmaceuticals. It has also been studied for its potential as an antifungal agent and for its antimicrobial activity. Additionally, 5-BROMO-1-METHYL-2(1H)-PYRIDINONE has been investigated for its potential use in creating new materials and as a key component in fluorescent dyes. Overall, this compound is valued for its versatility and wide-ranging potential in various industries.

Upstream product

• 694-85-9 1-methyl-2-pyridone 

Downstream Products

• 946619-94-9 C₄₁H₄₁F₄N₅O₆S 
• 1114088-38-8 (R)-6-(3-hydroxypropyl)-3-((S)-1-(4-(1-methyl-6-oxo-1,6-dihydropyridin-3-yl)phenyl)ethyl)-6-phenyl-1,3-oxazinan-2-one 
• 1349798-35-1 5-bromo-1-methyl-3-phenylpyridin-2(1H)-one 
• 1349798-36-2 C₁₂H₁₁NO₂ 
• 1349798-32-8 C₂₀H₂₆N₂O₂ 
• 1349798-37-3 C₁₅H₁₆ClNO₂ 
• 1193334-38-1 (S)-6-(2-fluorophenyl)-6-(2-hydroxy-2-methylpropyl)-3-((S)-1-(4-(1-methyl-6-oxo-1,6-dihydropyridin-3-yl)phenyl)ethyl)-1,3-oxazinan-2-one 
• 1114558-37-0 (S)-6-(4-fluorophenyl)-6-(2-hydroxy-2-methylpropyl)-3-((S)-1-(4-(1-methyl-6-oxo-1,6-dihydropyridin-3-yl)phenyl)ethyl)-1,3-oxazinan-2-one 
• 1114562-01-4 2,2-dimethyl-3-((R)-3-((S)-1-(4-(1-methyl-6-oxo-1,6-dihydropyridin-3-yl)phenyl)ethyl)-2-oxo-6-phenyl-1,3-oxazinan-6-yl)propanenitrile 
• 1114558-92-7 (S)-6-(2-hydroxy-2-methylpropyl)-3-((S)-1-(4-(1-methyl-6-oxo-1,6-dihydropyridin-3-yl)phenyl)ethyl)-6-phenyl-1,3-oxazinan-2-one 
• 1219741-55-5 1-methyl-5-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]pyridin-2(1H)-one 
• 1172022-21-7 5-(4-((S)-1-((S)-4-allyl-4-(4-fluorophenyl)-2-oxopiperidin-1-yl)ethyl)phenyl)-1-methylpyridin-2(1H)-one 
• 889865-35-4 5-[4-(1-t-butoxycarbonylpiperidin-4-yloxy)phenyl]-1-methyl-2(1H)-pyridone 
• 889865-33-2 5-{4-(3-chloropropoxy)phenyl}-1-methyl-2(1H)-pyridone 

Relevant articles and documents

Iridium-Catalysed C-H Borylation of 2-Pyridones; Bisfunctionalisation of CC4

The high regioselectivity associated with the iridium-catalysed borylation of pyridones has been exploited to provide a very direct and efficient entry to C(10) doubly substituted CC4 variants of cytisine. Two approaches have been evaluated based on (i) C-H activation of cytisine (or an N-substituted derivative) followed by N-alkylation (to enable dimer formation) and (ii) direct C-H activation and borylation of CC4 itself. Both approaches provide access to C(10)-functionalized CC4 derivatives, but direct borylation of CC4 allows for a wider range of functional group interconversions to be tolerated.