81976-28-5

Basic information

• Product Name: 2,8-Bis-(3,4-dichloro-phenyl)-1,7-dihydro-purin-6-one
• CAS NO: 81976-28-5
• Molecular Weight: 426.089
• Mol File: 81976-28-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2,8-Bis-(3,4-dichloro-phenyl)-1,7-dihydro-purin-6-one(CAS DataBase Reference)
• NIST Chemistry Reference: 2,8-Bis-(3,4-dichloro-phenyl)-1,7-dihydro-purin-6-one(81976-28-5)
• EPA Substance Registry System: 2,8-Bis-(3,4-dichloro-phenyl)-1,7-dihydro-purin-6-one(81976-28-5)

Safety Data

• Hazardous Substances Data: 81976-28-5(Hazardous Substances Data)

Upstream product

• 6285-64-9 phenylazomalonamamidine hydrochloride 
• 6287-38-3 3,4-dichlorobenzaldehyde 

Relevant articles and documents

A ONE-STEP SYNTHESIS OF PURINE DERIVATIVES BY THE REACTION OF PHENYLAZOMALONAMIDAMIDINE WITH ARYL ALDEHYDES

Treatment of phenylazomalonamidamidine (I) with aryl aldehydes yielded the corresponding 2,8-diarylhypoxanthines (II) in single step.The reaction under milder conditions formed the intermediary monoarylidene derivatives (III) of I, from which the corresponding 6-amino-2-aryl-5-phenylazopyrimidine-4(3H)-ones (IV) were obtained by the oxidative cyclization with diethyl azodicarboxylate.Treatment of IV with second aryl aldehydes gave the unsymmetrical 2,8-diarylated hypoxanthines.