819798-05-5Relevant academic research and scientific papers
Total Synthesis of the Lipid-Anchor-Attached Core Trisaccharides of Lipoteichoic Acids of Streptococcus pneumoniae and Streptococcus oralis Uo5
Ghotekar, Balasaheb K.,Kulkarni, Suvarn S.,Podilapu, Ananda Rao
, (2020/02/04)
Herein we report an efficient total synthesis of lipid-anchor-appended core trisaccharides of lipoteichoic acids of Streptococcus pneumoniae and Streptococcus oralis Uo5. The key features include the expedient synthesis of the rare sugar 2,4,6-trideoxy-2-acetamido-4-amino-d-Galp building block via one-pot sequential SN2 reactions and the α-selective coupling of d-thioglucoside with the diacyl glycerol acceptor to construct a common disaccharide acceptor, which was utilized in the total synthesis of target molecules 1 and 2.
Synthesis of a library of fucopyranosyl-galactopyranosides consisting of a complete set of anomeric configurations and linkage positions
Ohtsuka, Isao,Ako, Takuro,Kato, Rumiko,Daikoku, Shusaku,Koroghi, Satomi,Kanemitsu, Takuya,Kanie, Osamu
, p. 1476 - 1487 (2007/10/03)
A library composed of a complete set of fucopyranosyl-galactopyranosides was synthesized. A perbenzylated phenylthio fucopyranoside and a series of tri-O-benzyl-galactopyranosyl fluorides having single hydroxyl groups at the 2-, 3-, 4-, and 6-positions we
METHOD OF SYNTHESIZING SUGAR CHAIN
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Page/Page column 18, (2010/11/08)
An object of the present invention is to provide a method for efficiently chemically synthesizing biomolecules including a nucleotide (nucleic acid), a peptide (protein), or a sugar chain, as representative examples. The present invention provides a metho
