82019-32-7

Usage

Uses

Used in Pharmaceutical Industry:
7-Bromo-1-methyl-1H-quinoxalin-2-one is used as a chemical compound for the development of new drugs due to its quinoxaline structure, which may possess biological activities beneficial for medicinal applications.
Used in Specialty Chemicals Production:
In the chemical industry, 7-Bromo-1-methyl-1H-quinoxalin-2-one is used as a component in the production of specialty chemicals, where its unique structure and properties can contribute to the creation of advanced materials.
Used as a Research Reagent:
7-Bromo-1-methyl-1H-quinoxalin-2-one serves as a research reagent in scientific studies, aiding researchers in understanding its chemical properties and exploring its potential applications in various fields.

InChI:InChI=1/C9H7BrN2O/c1-12-8-4-6(10)2-3-7(8)11-5-9(12)13/h2-5H,1H3

Upstream product

• 82031-32-1 7-bromo-1H-quinoxalin-2-one 
• 1575-37-7 4-Bromo-benzene-1,2-diamine 
• 1196-57-2 quinoxalin-2⁽¹⁾-one 
• 74-88-4 methyl iodide 

Downstream Products

• 1225322-60-0 7-bromo-3-(tert-butyl)-1-methylquinoxalin-2(1H)-one 
• 85728-45-6 7-Bromo-1-methyl-3-(2-oxo-propyl)-1H-quinoxalin-2-one 
• 1225322-58-6 7-bromo-3-isopropyl-1-methylquinoxalin-2(1H)-one 

Relevant academic research and scientific papers

Metal-Free Direct Oxidative C?N Bond Coupling of Quinoxalin-2(1H)-ones with Azoles under Mild Conditions

Direct C3?H amination of quinoxalin-2(1H)-ones with azoles under mild conditions promoted by PIFA has been achieved in good yield in a very fast manner. Mechanistic study revealed that the reaction proceeds through a radical process. In addition, this method could be applied to gram-scale reaction.

Synthesis of (E)-Quinoxalinone Oximes through a Multicomponent Reaction under Mild Conditions

Herein, a novel method for the gram-scale synthesis of (E)-quinoxalinone oximes through a multicomponent reaction under mild conditions is described. Such a transformation was performed under transition-metal-free conditions, affording (E)-oximes in a moderate-to-good yield through recrystallization. Our methodology demonstrates a successful combination of a Mannich-type reaction and radical coupling, providing a green and practical approach for the synthesis of potentially bioactive quinoxalinone-containing molecules.

HETEROCYCLIC SULFONAMIDES AS RAF INHIBITORS

Compounds of Formula (I) are useful for inhibition of Raf kinases. Methods of using compounds of Formula (I), stereoisomers, tautomers and pharmaceutically acceptable salts thereof, for in vitro, in situ, and in vivo diagnosis, prevention or treatment of such disorders in mammalian cells, or associated pathological conditions are disclosed.

FUSED PYRAZOLE DERIVATIVES AS TGF-BETA SIGNAL TRANSDUCTION INHIBITORS FOR THE TREATMENT OF FIBROSIS AND NEOPLASMS

The disclosed invention is directed to compounds of the formula: Formula (I) and methods of using these compounds.