820253-14-3

Upstream product

• 74866-28-7 2,2'-dibromo-1,1'-binaphthyl 
• 820253-12-1 bis[3,5-bis(trifluoromethyl)phenyl]phosphinyl chloride 
• 142421-57-6 bis(3,5-di(trifluoromethyl)phenyl)chlorophosphine 
• 159418-71-0 [di-3,5-bis(trifluoromethyl)phenyl](diethyl-amino)phosphine 
• 112981-69-8 3,5-bis(trifluoromethyl)phenylmagnesium bromide 

Relevant academic research and scientific papers

Improved syntheses of phosphine ligands by direct coupling of diarylbromophosphine with organometallic reagents

Br versus Cl: It is found that the use of diarylbromophosphines instead of diarylchlorophosphines is crucial for their direct coupling with binaphthylmagnesium bromide or BINOL triflate. This finding has led to an improved preparation of both electron-deficient BINAP-type phosphine ligands and several important Buchwald's ligands. Copyright

Stereospecific deoxygenation of phosphine oxides with retention of configuration using triphenylphosphine or triethyl phosphite as an oxygen acceptor

(Chemical Equation Presented) A new protocol for deoxygenation of various phosphine oxides with retention of configuration is described. The advantage of the new method includes milder conditions and considerably shortened reaction times. Mechanistic studies about the oxygen transfer between the starting phosphine oxide and the sacrificial triphenylphosphine are also presented.