82049-96-5 Usage
Chemical structure
Pyrrolidinone derivative with a trifluoromethoxyphenyl group attached to the pyrrolidinone ring
Application
Commonly used in the synthesis of pharmaceuticals and agrochemicals
Reactivity
Versatile reactivity due to the presence of the trifluoromethoxy group on the phenyl ring
Biological activities
Potential biological activities, making it valuable for research and development in the pharmaceutical and agricultural industries
Intermediate
Acts as an intermediate in the production of various organic compounds
Chemical properties
The trifluoromethoxy group on the phenyl ring contributes to the compound's chemical properties, enhancing its value in research and development
Check Digit Verification of cas no
The CAS Registry Mumber 82049-96-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,2,0,4 and 9 respectively; the second part has 2 digits, 9 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 82049-96:
(7*8)+(6*2)+(5*0)+(4*4)+(3*9)+(2*9)+(1*6)=135
135 % 10 = 5
So 82049-96-5 is a valid CAS Registry Number.
82049-96-5Relevant articles and documents
Aluminium Chloride-Mediated Synthesis of 1-Chloro-2,2,2-Trifluoroethylidene-Substituted Pyrrolidones
Wang, Zeng,Yuan, Zihang,Han, Xiaoyan,Weng, Zhiqiang
, p. 2178 - 2182 (2018)
An aluminium chloride-mediated cascade reaction between pyrrolidones and trifluoroacetic anhydride is reported. Functionally diverse 1-chloro-2,2,2-trifluoroethylidene-substituted pyrrolidones were obtained in moderate to high yields through electrophilic trifluoroacetylation, nucleophilic chlorination, and elimination. This procedure has a wide scope, good functional-group tolerance and the reaction conditions are amenable to scale up. Additionally the obtained 1-chloro-2,2,2-trifluoroethylidene products can be applied to further functionalization as trifluoromethyl-containing building blocks. Some of the title compounds showed fungicidal activity against cucumber downy mildew (CDM). (Figure presented.).
