82064-77-5Relevant articles and documents
Synthesis of Highly Substituted Phenols and Benzenes with Complete Regiochemical Control
Zhang, Xiaojie,Beaudry, Christopher M.
supporting information, p. 6086 - 6090 (2020/08/12)
Substituted phenols are requisite molecules for human health, agriculture, and diverse synthetic materials. We report a chemical synthesis of phenols, including penta-substituted phenols, that accommodates programmable substitution at any position. This method uses a one-step conversion of readily available hydroxypyrone and nitroalkene starting materials to give phenols with complete regiochemical control and in high chemical yield. Additionally, the phenols can be converted into highly and even fully substituted benzenes.
Synthesis of functionalized salicylates by formal [3+3] cyclocondensation of 1,3-bis(silyloxy)buta-1,3-dienes with 3-alkoxy-2-en-1-ones
Mross, Gerson,Ladzik, Simone,Reinke, Helmut,Spannenberg, Anke,Fischer, Christine,Langer, Peter
experimental part, p. 2236 - 2248 (2009/12/26)
The formal [3+3] cyclization of 1,3-bis(silyloxy)buta-1,3-dienes with 1-aryl-3-ethoxyprop-2-en-1-ones, available by Heck reaction of benzoyl chlorides with ethyl vinyl ether, afforded a variety of 6-arylsalicylates. The reaction of the products with conce
A straightforward entry into polyketide monoprenylated furanocoumarins and pyranocoumarins
Appendino, Giovanni,Cravotto, Giancarlo,Giovenzana, Giovanni B.,Palmisano, Giovanni
, p. 1627 - 1631 (2007/10/03)
A regioselective synthesis of 5-methyl- and 5-ethyl-4- hydroxycoumarin (1b and 1c, respectively) is described. Starting from these compounds, several prenylated polyketide coumarins of limited availability from natural sources and important taxonomic relevance were prepared.
