82093-39-8Relevant academic research and scientific papers
Organotellurium Chemistry. 7. Reductive Removal of Electronegative α Substituents of Ketones and Acids by a Tellurolate Reagent
Engman, Lars,Cava, Michael P.
, p. 3946 - 3949 (1982)
Lithium and sodium 2-thiophenetellurolates have been used for the reductive dehalogenation of a variety of α-halo ketones and acids.Acetoxy, mesyloxy, and phenylthio groups were also successfully removed from the α position of an acetophenone.The reductions could in many cases be carried out by using sodium borohydride as the reducing agent in the presence of only a catalytic amount of the organotellurium reagent.Evidence is presented in support of a two-step mechanism involving the formation of α-aryltelluro carbonyl derivatives and enolate anions in succession.
