4198-15-6

Basic information

• Product Name: Benzenepropanamide, b-hydroxy-N-phenyl-
• CAS NO: 4198-15-6
• Molecular Formula: C15H15NO2
• Molecular Weight: 241.29
• Mol File: 4198-15-6.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: Benzenepropanamide, b-hydroxy-N-phenyl-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzenepropanamide, b-hydroxy-N-phenyl-(4198-15-6)
• EPA Substance Registry System: Benzenepropanamide, b-hydroxy-N-phenyl-(4198-15-6)

Safety Data

• Hazardous Substances Data: 4198-15-6(Hazardous Substances Data)

Upstream product

• 4894-23-9 3,5-diphenyl-4,5-dihydro-isoxazole 
• 108-24-7 acetic anhydride 
• 1213268-61-1 C₁₅H₁₅NO₂ 
• 100-52-7 benzaldehyde 
• 103-84-4 Acetanilid 
• 16717-64-9 1-azidostyrene 
• 100-42-5 styrene 
• 86217-47-2 3-phenyl-3-hydroxypropionic acid hydrazide 
• 5764-85-2 Ethyl 3-hydroxy-3-phenylpropanoate 
• 15463-91-9 3-bromo-3-phenylpropionic acid 
• 5326-87-4 N-(phenyl)bromoacetamide 
• 959-66-0 3-oxo-3-phenylpropionanilide 
• 82093-39-8 α-(2-thienyltelluro)acetanilide 
• 62-53-3 aniline 

Downstream Products

• 1018832-89-7 (S)-3-hydroxy-N,3-diphenylpropanamide 
• 1018832-83-1 C₂₂H₁₉NO₃ 
• 890411-58-2 1,2-diphenylazetidine 
• 80095-85-8 (E)-N,3-diphenylprop-2-enethioamide 
• 13474-22-1 1,4-diphenyl-azetidin-2-one 
• 3056-73-3 cinnamanilide 
• 4888-31-7 3-Acetoxy-3-phenyl-propionsaeure-anilid 

Relevant articles and documents

Amide synthesis by nucleophilic attack of vinyl azides

A method for the synthesis of amide-containing molecules was developed using vinyl azides as an enamine-type nucleophile towards carbon electrophiles, such as imines, aldehydes, and carbocations that were generated from alcohols in the presence of BF3OEt2. After nucleophilic attack of the vinyl azide, a substituent of the resulting iminodiazonium ion intermediate migrates to form a nitrilium ion, which is hydrolyzed to afford the corresponding amide. Nitrilium intermediate: A new method for amide synthesis employs vinyl azides as enamine-type nucleophiles towards carbon electrophiles in the presence of BF3OEt2. After nucleophilic attack of the vinyl azide, a substituent of the resulting iminodiazonium ion intermediate A migrates to form nitrilium ion B, which is hydrolyzed to afford the corresponding amide.

Efficient and regioselective synthesis of 5-hydroxy-2-isoxazolines: Versatile synthons for isoxazoles, β-lactams, and γ-amino alcohols

"Chemical Equation Presented" An efficient and highly regioselective protocol was developed for the preparation of 5-hydroxy2-isoxazolines, which have been proved to be versatile synthons for isoxazles, β-hydroxy oximes, and γ-amino alcohols. β-Lactams, commonly embedded in the skeletons of bioactive natural products, were also synthesized in two steps from β-hydroxy oximes, providing a new strategy for the synthesis of this kind of compounds.

Stereospecific cyclization of β-hydroxy aryl amides to β-lactams

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