82100-22-9

Upstream product

• 112030-62-3 3-(4-Bromo-phenyl)-3-oxo-propionimidic acid ethyl ester; hydrochloride 
• 107-15-3 ethylenediamine 
• 57367-05-2 1-(4-bromophenyl)-3,3-dimercapto-2-propen-1-one 
• 99-73-0 para-bromophenacyl bromide 
• 4592-94-3 3-(4-bromophenyl)-3-oxopropanenitrile 
• 39580-38-6 1-(4-bromophenyl)-3,3-bis(methylthio)prop-2-en-1-one 
• 82100-51-4 1-(4-bromo-phenyl)-2-(4,5-dihydro-1H-imidazol-2-ylsulfanyl)-ethanone 

Downstream Products

• 136271-20-0 1-(4-Bromo-phenyl)-2-(2,4-dinitro-phenylazo)-2-imidazolidin-2-ylidene-ethanone 
• 1450991-99-7 C₂₀H₁₇BrN₂O₂ 
• 136271-19-7 1-(4-Bromo-phenyl)-2-imidazolidin-2-ylidene-2-(2-nitro-phenylazo)-ethanone 
• 112030-67-8 1-(4-Bromo-phenyl)-2-(4,5-dihydro-1H-imidazol-2-yl)-ethanone; hydrochloride 

Relevant academic research and scientific papers

Multicomponent Cascade Reaction by Metal-Free Aerobic Oxidation for Synthesis of Highly Functionalized 2-Amino-4-coumarinyl-5-arylpyrroles

A novel approach has been constructed for the synthesis of two types of 2-amino-4-coumarinyl-5-arylpyrroles (ACAPs, 5 and 6) through a cascade reaction and a metal-free catalyzed aerobic oxidation reaction of arylglyoxal monohydrates 1, 1,1-enediamines (E

Multicomponent Tether Catalysis Synthesis of Highly Functionalized 4-(Pyridin-2-ylmethyl)-2-aminopyrroles via Cascade Reaction Is Accompanied by Decarboxylation

A multicomponent tether catalysis protocol for the synthesis of 4-(pyridin-2-ylmethyl)-2-aminopyrroles (PMAPs) was constructed by simply refluxing a mixture of ethyl 2-(pyridin-2-yl)acetates 1 and various types of arylglyoxal monohydrates 2 and different heterocyclic ketene aminals 3 in EtOH solvent. Based on this reaction, a series of highly functionalized PMAPs were obtained through a novel cascade reaction accompanied by a decarboxylation mechanism. As a result, the pyridin-2-ylmethyl was successfully introduced in the target compounds, and a library of PMAPs were easily constructed using the cascade reaction described in this study. This protocol demonstrated that the most important feature was the decarboxylation reaction of the 2-(pyridin-2-yl)acetates 1, which can be used in the synthesis of pyridin-2-ylmethyl-substituted heterocycles, including pyrroles, pyridines, quinolones, and other heterocyclic compounds resembling those found in nature.

Synthesis of Partially Reduced Imidazo[1,2- a ]pyridines through an Unprecedented Base-Mediated (4+2) Cyclization

A water-mediated regioselective synthesis of 6,7-diaryl-5-oxo-2,3,5,6-tetrahydroimidazo[1,2-a]pyridine-6-carbonitriles was performed by the reaction of 2-[1-cyano-2,2-bis(methylsulfanyl)vinyl]benzonitrile with 1-aryl-2-(imidazolidin-2-ylidene)ethanones un

Synthesis of imidazo[1,2-a]pyridines and pyrido[1,2-a]pyrimidines in water and their snar cyclizations

Synthesis of tetrahydroimidazo[1,2-a]pyridines and tetrahydropyrido[1,2-a] pyrimidines by a one-pot and three component reaction of α-oxoketenedithioacetals, diamines and DMAD in water has been described. Different routes for accessing the desired compoun

Synthesis of annelated [a]aza-anthracenones and thieno[3,2-g]aza- naphthalenones through ring transformation of 2H-pyran-2-one followed by photocyclization

A concise synthesis of some new classes of heterocycles (4-aryl-11-oxo-1,2,3,11-tetrahydro-1,3a-diaza-cyclopenta[a]anthracen-6- carbonitriles and 5-aryl-12-oxo-1,3,4,12-tetrahydro-2H-1,4a-diazabenzo[a] anthracene-7-carbonitriles) has been developed by the

Synthesis of 2-(Benzoylmethylene)imidazolidines and -hexahydropyrimidines by Condensation of Ethyl Benzoylacetimidates With 1,2-Ethanediamine or 1,3-Propanediamine, and Some Addition Reactions

Ethyl benzoylacetimidates react with 1,2-ethanediamine or 1,3-propanediamine in absolute ethanol to afford the 2-(benzoylmethylene)imidazolidines or -hexahydropyrimidines, respectively.The structure of these products as ketene aminals is confirmed by spec

Synthesis of 1,1-Diamino-2-acylethylenes - Sulphide Contraction Route

Triphenylphosphine-induced sulphur extrusion from phenacylthioimidazolines, tetrahydropyrimidines and their benzo analogues has been used for the synthesis of a variety of 1,1-diamino-2-acylethylenes.