82101-33-5

Upstream product

• 2085-88-3 2-methyl-2-phenyloxirane 
• 536-74-3 phenylacetylene 
• 98-86-2 acetophenone 
• 6712-35-2 2-phenylpent-4-yn-2-ol 
• 591-50-4 iodobenzene 
• 106-96-7 propargyl bromide 
• 1794-48-5 1-bromo-3-phenylprop-2-yne 

Downstream Products

• 1338726-06-9 (E)-3-(1-(4-methoxyphenyl)ethylidene)-5-methyl-5-phenyldihydro-2(3H)-furanone 
• 1644563-22-3 5,5-diphenyl-4-(trifluoromethyl)pent-4-en-2-one 
• 36144-55-5 5,5-diphenylpenta-3,4-dien-2-one 
• 1072877-73-6 3-methyl-1,3-diphenyl-3H-naphtho[2,1-b]pyran 
• 62676-19-1 2,4-diphenylbut-1-en-3-yne 

Relevant academic research and scientific papers

TBAI/K2S2O8 Initiated Radical Cyclization to Synthesize β- Arylsulfonyl Naphthalenes from Homopropargylic Alcohols and Sulfonyl Hydrazides

A metal-free radical addition method for the synthesis of β-arylsulfonyl naphthalenes with homopropargylic alcohols and sulfonyl hydrazides has been developed. In this reaction, sulfonyl hydrazide is employed as the source of sulfonyl radical to produce the desired sulfone directly. There is the first example for homopropargylic alcohol through direct intramolecular addition of vinyl radical to arenes with sulfonyl radical, which is initiated by the TBAI/K2S2O8 reaction system and generates the desired products in moderate yields. (Figure presented.).

A Tetraarylpyrrole-Based Phosphine Ligand for the Palladium-Catalyzed Amination of Aryl Chlorides

A tetraarylpyrrole-based phosphine ligand L1 in combination with Pd(dba)2 provided a catalyst for the Buchwald-Hartwig amination reaction. A variety of amines were rapidly coupled with aryl chlorides at a Pd loading of 0.5 mol%. The selective monoarylation of aliphatic primary amines was achieved in the presence of 0.8 equiv. water. Comparison experiments were also conducted, which revealed that the catalytic activity of L1 is superior to representative phosphine ligands in the Pd-catalyzed C?N coupling of various amines. (Figure presented.).

PHOSPHINE COMPOUND, CROSSLINKED COMPOSITION, AND MANUFACTURING METHOD OF AROMATIC AMINE COMPOUND

PROBLEM TO BE SOLVED: To provide a phosphine compound capable of constituting a transition metal complex excellent in reaction speed and selectivity as a catalyst. SOLUTION: There is provided a phosphine compound represented by the formula (I). In the formula Ar represents each independently an aryl group which may be substituted, R1 represents each independently a linear, branched or cyclic alkyl group, R2 represents each independently a linear, branched or cyclic alkyl group, alkoxy group or aryl group which may be substituted, or neighboring 2 R2 are bound each other to form a ring, and n represents an integer of 0 to 4. SELECTED DRAWING: None COPYRIGHT: (C)2020,JPOandINPIT

Tetra-substituted olefin and preparation method thereof

The invention discloses tetra-substituted olefin and a preparation method thereof. The method takes a compound shown as a formula I and diethyl bromomalonate as raw materials, and the raw materials are illuminated by white light to react under the action of a photocatalyst and alkali; after reaction is finished, a compound shown as a formula II is obtained. The method has the advantages of moderate conditions, simplicity in operation, no strict requirements on equipment and high product yield; visible light is used for inducing the reaction; the raw materials are cheap and easy to obtain and asubstrate has a wide applicable range and can tolerate a lot of organic functional groups.

Copper-catalyzed one-pot trifluoromethylation/aryl migration/carbonyl formation with homopropargylic alcohols

A novel copper-catalyzed one-pot functionalization of homopropargylic alcohols that involves trifluoromethylation, aryl migration, and formation of a carbonyl moiety has been developed. This reaction constitutes the first direct conversion of homopropargy

Silver-catalyzed intramolecular chloroamination of allenes: Easy access to functionalized 3-pyrroline and pyrrole derivatives

A 1,10-phenanthroline-ligated cationic silver complex allows the intramolecular chloroamination of allenes with N-chlorosuccinimide using 2,6-lutidine as a base. This process proceeds under mild conditions and can tolerate a variety of functional groups.

MASS SPECTRA OF TERTIARY β-ACETYLENIC ALCOHOLS

The fragmentation of the molecular ions in the mass spectra of tertiary β-acetylenic alcohols (the products from the reaction of a series of disubstituted unsymmetrical oxiranes with lithium phenylacetylide in a mixture of hexamethylphosphorotriamide and benzene) was investigated.It was shown that one of the main primary processes in the dissociation of the molecular ions of the investigated compounds under electron impact is elimination of a neutral molecule of the carbonyl compound in a process of the McLafferty rearrangement type.