82101-34-6

Basic information

• Product Name: 4-(2-Fluorophenyl)-3,4-dihydronaphthalen-1(2H)-one
• Synonyms: 4-(2-Fluorophenyl)-3,4-dihydronaphthalen-1(2H)-one;4-(2-Fluorophenyl)-3,4-dihydro-1(2H)-naphthalenone;-3,4-dihydronaphthalen-1(2H);4-(2-Fluorophenyl)
• CAS NO: 82101-34-6
• Molecular Formula: C₁₆H₁₃FO
• Molecular Weight: 240.2722232
• Mol File: 82101-34-6.mol

Chemical Properties

• Appearance: /
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 4-(2-Fluorophenyl)-3,4-dihydronaphthalen-1(2H)-one(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(2-Fluorophenyl)-3,4-dihydronaphthalen-1(2H)-one(82101-34-6)
• EPA Substance Registry System: 4-(2-Fluorophenyl)-3,4-dihydronaphthalen-1(2H)-one(82101-34-6)

Safety Data

• Hazardous Substances Data: 82101-34-6(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
4-(2-Fluorophenyl)-3,4-dihydronaphthalen-1(2H)-one is used as a pharmaceutical candidate for its anti-inflammatory and analgesic properties, which can be beneficial in the development of new medications to treat pain and inflammation.
Used in Medicinal Chemistry Research:
4-(2-Fluorophenyl)-3,4-dihydronaphthalen-1(2H)-one is utilized in medicinal chemistry research to explore its potential as a lead molecule for the development of new drugs, given its unique structural features and pharmacological activities.
Used in Drug Development:
4-(2-Fluorophenyl)-3,4-dihydronaphthalen-1(2H)-one is employed in drug development for its potential to be optimized and modified to create more effective and safer medications, particularly in the areas of pain management and inflammation control.

Upstream product

• 462-06-6 fluorobenzene 
• 90-15-3 α-naphthol 

Downstream Products

• 85904-24-1 4-(2-fluorophenyl)-1-tetralone oxime 

Relevant articles and documents

Triazolo benzazepines

There are presented benzazepines of the formula STR1 wherein either R1 is hydrogen, lower alkyl, 4-pyridyl or the group --(CH2)n --NR6 R7 and R2 and R3 together are an additional bond or R1 and R2 together are the oxo group and R3 is hydrogen or lower alkyl, R4 is phenyl, o-halophenyl or 2-pyridyl, R5 is halogen or nitro and either R6 is hydrogen or lower alkyl and R7 is hydrogen, lower alkyl, lower alkenyl or lower alkynyl or R6 and R7 together with the nitrogen atom are 4-(lower alkyl)-1-piperazinyl or 4-morpholinyl and n is the number 0 or 1, and their pharmaceutically acceptable acid additions salts. The compounds possess interesting psychotropic properties, i.e., pronounced anxiolytic properties have been established in the case of certain representative members of this class of substance.

REACTION OF PHENOLS AND THEIR DERIVATIVES WITH AROMATIC COMPOUNDS IN THE PRESENCE AF ACIDIC AGENTS. CONDENSATION OF 1-NAPHTHOL WITH MONOSUBSTITUTED DERIVATIVES OF BENZENE

The isomeric composition and the relative formation rates of 4-(X-phenyl)-1-tetralones in the condensation of 1-naphthol with C6H5X (X=CH3, F, Cl, H) in the presence of aluminum bromide were determined.The obtained date demonstrate the electrophilic character of the particle which is formed from 1-naphthol and subsequently enters into reaction with benzene or its derivatives.The character of electrophilic activation of the phenols and their ethers in condensation reactions of this type is discussed.