82117-35-9

Basic information

• Product Name: 3-(1-Piperazinyl)isoquinoline
• Synonyms: 3-(1-Piperazinyl)isoquinoline
• CAS NO: 82117-35-9
• Molecular Formula: C₁₃H₁₅N₃
• Molecular Weight: 213.28
• Product Categories: pharmacetical
• Mol File: 82117-35-9.mol
• Article Data: 4

Chemical Properties

• Melting Point: 95-96 °C
• Boiling Point: 417.7°C at 760 mmHg
• Flash Point: 206.4°C
• Appearance: /
• Density: 1.152g/cm³
• Vapor Pressure: 3.47E-07mmHg at 25°C
• Refractive Index: 1.628
• PKA: 8.63±0.10(Predicted)
• CAS DataBase Reference: 3-(1-Piperazinyl)isoquinoline(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(1-Piperazinyl)isoquinoline(82117-35-9)
• EPA Substance Registry System: 3-(1-Piperazinyl)isoquinoline(82117-35-9)

Safety Data

• Hazardous Substances Data: 82117-35-9(Hazardous Substances Data)

Usage

InChI:InChI=1/C13H15N3/c1-2-4-12-10-15-13(9-11(12)3-1)16-7-5-14-6-8-16/h1-4,9-10,14H,5-8H2

Upstream product

• 25475-67-6 isoquinolin-3-amine 
• 689-98-5 chloroethylamine 
• 110-85-0 piperazine 
• 19493-45-9 3-chloroisoquinoline 
• 1042986-15-1 tert-butyl 4-(isoquinolin-3-yl)piperazine-1-carboxylate 

Downstream Products

• 1061517-17-6 C₃₁H₂₉N₅O₂ 
• 1310087-47-8 C₃₂H₂₉N₅O₂ 
• 1309079-99-9 C₃₀H₃₃N₅O₃ 
• 1350969-09-3 C₃₂H₃₆N₄O₃ 
• 82117-51-9 Cinuperone 
• 82117-68-8 3-(4-(4-Methoxybenzoyl)-piperazin-1-yl)-isoquinoline 
• 82117-65-5 3-(4-[4,4-bis-(4-Fluorophenyl)-butyl]-piperazin-1-yl)-isoquinoline 

Relevant articles and documents

Pd-Catalyzed Synthesis of Piperazine Scaffolds under Aerobic and Solvent-Free Conditions

A facile Pd-catalyzed methodology providing an efficient synthetic route to biologically relevant arylpiperazines under aerobic conditions is reported. Electron donating and sterically hindered aryl chlorides were aminated to afford yields up to 97%, with examples using piperazine as solvent, illustrating an ecofriendly, cost-effective synthesis of these privileged structures.

KINASE INHIBITORS

-