82131-11-1Relevant academic research and scientific papers
H-Bonding-promoted radical addition of simple alcohols to unactivated alkenes
Tian, Yunfei,Liu, Zhong-Quan
, p. 5230 - 5235 (2017/11/09)
H-Bonding-induced radical addition of simple alcohols to unactivated olefins was achieved. It effectively solved the long-standing problems of reactivity and selectivity in this type of reaction. The hydroxyalkylation occurred via site-specific cleavage of the α-hydroxyl-C-H bond in alcohols. This method allows a highly atom-economical, operationally simple and environmentally benign access to diverse primary, secondary and tertiary alcohols, diols, and even polyfluorinated alcohols. These useful chemicals are traditionally synthesized by using commercially unavailable organometallics via complex operations. In contrast, they can be facilely obtained through this protocol utilizing widely available starting materials.
SELECTIVE CLEAVAGE OF ETHERS BY SODIUM IODIDE - ACYL CHLORIDE
Oku, Akira,Harada, Toshiro,Kita, Kazuhiro
, p. 681 - 684 (2007/10/02)
Cyclic and acyclic ethers are regioselectively cleavaged at less substituted α-carbon-oxygen bond in the absence of Lewis acid by the reagent system of sodium iodide and acyl chlorides.
