82139-93-3

Upstream product

• 34209-81-9 Acetic acid (3S,8R,9S,10R,13S,14S,16R,17S)-17-acetyl-10,13-dimethyl-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-20-oxa-cyclopropa[16,17]cyclopenta[a]phenanthren-3-yl ester 
• 4059-78-3 3β-acetoxy-16α-hydroxy-pregn-5-en-20-one 
• 98-88-4 benzoyl chloride 

Downstream Products

• 82139-94-4 18,20-epoxy-20-ethoxypregn-5-ene-3β,16α-diol 3-acetate 16-benzoate 
• 82139-96-6 Benzoic acid (3S,8R,9S,10R,13R,14S,16R,17R)-3-acetoxy-17-acetyl-13-iodomethyl-10-methyl-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-16-yl ester 
• 82149-51-7 Benzoic acid (3S,8R,9S,10R,13R,14S,16R,17S)-3-acetoxy-17-((R)-1-hydroxy-ethyl)-13-iodomethyl-10-methyl-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-16-yl ester 
• 82139-95-5 3β-acetoxy-16α-benzoyloxypregn-5-en-20β-ol 

Relevant academic research and scientific papers

18-Substituted Steroids. Part 10. Synthesis of 16α,18,21-Trihydroxypregn-4-ene-3,20-dione (16α,18-Dihydroxy-11-deoxycorticosterone)

The title compound has been prepared from 3β-acetoxy-16α-hydroxypregn-5-en-20-one by two routes, each involving application of the 'hypoiodite' reaction sequence to a 16α-acyloxypregnan-20β-ol derivative, to obtain