82174-41-2

Basic information

• Product Name: 1,1-bis(4-fluorophenyl)propan-2-one
• Synonyms: 1,1-bis(4-fluorophenyl)propan-2-one
• CAS NO: 82174-41-2
• Molecular Weight: 246.256
• Mol File: 82174-41-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1,1-bis(4-fluorophenyl)propan-2-one(CAS DataBase Reference)
• NIST Chemistry Reference: 1,1-bis(4-fluorophenyl)propan-2-one(82174-41-2)
• EPA Substance Registry System: 1,1-bis(4-fluorophenyl)propan-2-one(82174-41-2)

Safety Data

• Hazardous Substances Data: 82174-41-2(Hazardous Substances Data)

Upstream product

• 67-64-1 acetone 
• 460-00-4 1-Bromo-4-fluorobenzene 

Downstream Products

• 99734-06-2 α,α-bis(4-fluorophenyl)allyl alcohol 

Relevant articles and documents

Palladium-catalyzed amination of aromatic C-H bonds with oxime esters

"Chemical equation presented" We report a conceptually new approach to the direct amination of aromatic C-H bonds. In this process, an oxime ester function reacts with an aromatic C-H bond under redox-neutral conditions to form, in the case studied, an indole product. These reactions occur with relatively low catalyst loading (1 mol %) by a mechanism that appears to involve an unusual initial oxidative addition of an N-O bond to a Pd(0) species. The Pd(II) complex from oxidative addition of the N-X bond has been isolated for the first time, and evidence for the intermediacy of such oxidative addition products in the catalytic reaction has been gained.