821799-10-4

Upstream product

• 821799-09-1 (1S,9S)-(10,10-dimethyl-6-aza-tricyclo[7.1.1.0^2,7]undeca-2⁽⁷⁾,3,5-trien-5-yl)-methanol 
• 821799-04-6 (1S,9S)-10,10-dimethyl-6-aza-tricyclo[7.1.1.0^2,7]undeca-2⁽⁷⁾,3,5-triene-5-carboxylic acid methyl ester 
• 821799-03-5 (1S,9S)-5-furan-2-yl-10,10-dimethyl-6-aza-tricyclo[7.1.1.0^2,7]undeca-2⁽⁷⁾,3,5-triene 
• 946-07-6 1-(2-(furan-2-yl)-2-oxoethyl)pyridinium bromide 
• 15109-94-1 1-(2-furyl)-2-bromoethanone 

Downstream Products

• 821799-06-8 1-((1S,9S)-10,10-dimethyl-6-aza-tricyclo[7.1.1.0^2,7]undeca-2⁽⁷⁾,3,5-trien-5-yl)-ethanone 
• 821799-11-5 1-((1S,9S)-10,10-dimethyl-6-aza-tricyclo[7.1.1.0^2,7]undeca-2⁽⁷⁾,3,5-trien-5-yl)-ethanol 

Relevant academic research and scientific papers

Synthesis of a C2-symmetric chiral bipyridyldiol ligand and its application in the enantioselective addition of diethylzinc to substituted benzaldehydes

Herein the synthesis of a novel C2-symmetric ligand comprising of a central bipyridine-pinene-derived core and two functionalized diphenylmethanol subunits is described. [8′-(Hydroxy-diphenyl-methyl)-10, 10,10′,10′-tetramethyl-[5,5′]bi[6-aza-tr

Synthesis and characterization of highly conjugated, chiral bridging ligands

This paper describes the synthesis of four chiral derivatives of the electronically highly conjugated tetra-2-pyridylpyrazine (TPPZ) bridging ligand, which are denoted (R)- and (S)-4,5- and 5,6-pineno-tetra-2-pyridylpyrazine (PTPPZ). Preparation of these ligands was undertaken through the use of commercially available, enantiomerically pure (1R)- and (1S)-α-pinene, which was functionalized and subsequently employed in a Kroehnke pyridine synthesis involving a furan-substituted pyridinium salt to yield a chiral, furan-substituted pyridyl intermediate. Oxidative degradation and subsequent reduction of this furan led to a chiral, substituted 2-pyridylaldehyde, which underwent a pyridoin condensation followed by cyclization to produce the final PTPPZ ligands.