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Halofuginone Lactate is a halogenated derivative of febrifugine, a natural quinazolinone-containing compound found in the Chinese herb D. febrifuga.
Used in Veterinary Medicine:
Halofuginone Lactate is used as an antiprotozoal and a coccidiostat for the treatment and prevention of coccidiosis in animals.
Used in Pharmaceutical Industry:
Halofuginone Lactate is used as a potential treatment for scleroderma, a chronic connective tissue disease, and has received orphan drug designation from the U.S. Food and Drug Administration.
Used in Animal Husbandry:
Halofuginone Lactate is used in combination with disinfection methods, such as p-chloro-m-cresol, to control natural cryptosporidiosis in calves.

82186-71-8

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82186-71-8 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 82186-71-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,2,1,8 and 6 respectively; the second part has 2 digits, 7 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 82186-71:
(7*8)+(6*2)+(5*1)+(4*8)+(3*6)+(2*7)+(1*1)=138
138 % 10 = 8
So 82186-71-8 is a valid CAS Registry Number.
InChI:InChI=1/C16H17BrClN3O3.C3H6O3/c17-11-6-13-10(5-12(11)18)16(24)21(8-20-13)7-9(22)4-14-15(23)2-1-3-19-14;1-2(4)3(5)6/h5-6,8,14-15,19,23H,1-4,7H2;2,4H,1H3,(H,5,6)/t14?,15-;/m1./s1

82186-71-8SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017

1.Identification

1.1 GHS Product identifier

Product name HALOFUGINONE LACTATE

1.2 Other means of identification

Product number -
Other names halofuginonlactat

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:82186-71-8 SDS

82186-71-8Downstream Products

82186-71-8Relevant academic research and scientific papers

Synthetic method for halofuginone and intermediate of halofuginone

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Paragraph 0280-0282, (2019/11/28)

The invention relates to a synthetic method for halofuginone and an intermediate of the halofuginone. The reaction formula is shown in the description, wherein R1 is one selected from the group consisting of methyl, ethyl, n-propyl, isopropyl and t-butyl; R2 is one selected from the group consisting of methyl and ethyl; and R3 is one selected from the group consisting of methoxyformyl, ethoxyformyl, tert-butoxyformyl, benzyloxyformyl, trichloroethoxyformyl and benzyl. The synthetic method provided by the invention has the advantages of a simple process, low costs, few by-products in the synthetic process, a simple purification process, no need of column chromatography purification, a high product yield, less impurities, high purity, and controllable product quality, easily meets ICH declaration requirements and can be used for industrial production of the halofuginone.

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