82194-25-0

Upstream product

• 82194-21-6 5-Methoxy-2-methyl-2-phenyl-tetrahydro-furan 
• 6712-35-2 2-phenylpent-4-yn-2-ol 
• 98-86-2 acetophenone 
• 136050-77-6 2-phenyl-3,4-pentdien-2-ol 

Downstream Products

• 131259-11-5 (2S,4S,5R)-4,5-Dibromo-2-methyl-2-phenyl-tetrahydro-furan 
• 131259-11-5 (2S,4R,5R)-4,5-Dibromo-2-methyl-2-phenyl-tetrahydro-furan 
• 131259-11-5 (2S,4S,5S)-4,5-Dibromo-2-methyl-2-phenyl-tetrahydro-furan 
• 131259-11-5 (2S,4R,5S)-4,5-Dibromo-2-methyl-2-phenyl-tetrahydro-furan 
• 112359-43-0 4β,5β-dideuterio 2α-methyl 2β-phenyl tetrahydrofuran 
• 112359-43-0 4α,5α-dideuterio 2α-methyl 2β-phenyl tetrahydrofuran 
• 53774-21-3 5-methyl-5-phenyl-2,5-dihydrofuran-2-one 
• 1027560-55-9 5-methyl-5-phenyl-2,5-dihydro-furan-2-yl hydroperoxide 

Relevant academic research and scientific papers

Cooperative Metal-Ligand Catalyzed Intramolecular Hydroamination and Hydroalkoxylation of Allenes Using a Stable Iron Catalyst

A new iron-catalyzed chemoselective intramolecular hydroamination and hydroalkoxylation of the readily available α-allenic amines and alcohols to valuable unsaturated 5-membered heterocycles, 2,3-dihydropyrrole and 2,3-dihydrofuran, is reported. Effective

Selective and efficient cycloisomerization of alkynols catalyzed by a new ruthenium complex with a tetradentate nitrogen-phosphorus mixed ligand

The new ruthenium complex [Ru(N3P)(OAc)][BPh4] (4), in which N3P is the N,P mixed tetradentate ligand N,N-bis[(pyridin-2-yl)methyl]-[2(diphenylphosphino)phenyl]methanamine was synthesized. The complex was found to be catalytically active for the endo cycloisomerization of alkynols. The catalytic reactions can be used to synthesize five-, six-, and seven-membered endo-cyclic enol ethers in good to excellent yields. A catalytic cycle involving a vinylidene intermediate was proposed for the catalytic reactions. Treatment of complex 4 with PhC≡CH and H2O gave the alkyl complex [Ru(CH2PhJ(CO)(N 3P)][BPh4] (30), which supports the assumption that the catalytic reactions involve addition of a hydroxyl group to the C=C bond of vinylidene ligands.

Synthesis of α,β-unsaturated γ-lactones via photooxygenation of 2,3-dihydrofurans followed by ferrous ion-catalyzed gem-dehydration

Several alkyl and aryl substituted 2,3-dihydrofurans 1a-1e were synthesized and their reactions with singlet oxygen were investigated. Photooxygenation of 1a-1e in carbon tetrachloride at ambient temperature exclusively yields allylic hydroperoxides 4a-4e. Treatment of these hydroperoxides with aqueous ferrous sulfate solution affords the corresponding α,β-unsaturated γ-lactones 6a-6e with high yields. This work provides an efficient route to the preparation of butenolide moiety, an important functionality in the structures of many natural products that exhibit biological properties.

SYNTHESE DE COMPOSES DIHYDRO-2,3 FURANNIQUES PAR HYDROBORATION D'ALCOOLS β-ACETYLENIQUES

Hydroboration of β acetylenic alcohols followed by NaOH/H2O2 oxidation leads to hemiacetals of γ aldols which are easily dehydrated to 2,3-dihydrofuran compounds.The reaction gives good yields with hindered alcohols and its stereochemistry may be controlled during the organometallic synthesis of the starting alcohol.

A FACILE PREPARATION OF METHYL ENOL ETHERS FROM ACETALS AND KETALS USING TRIMETHYLSILYL IODIDE

Acetals and ketals are converted in high yields to the corresponding methyl vinyl ethers by treatment with trimethylsilyl iodide in the presence of hexamethyldisilazane at room temperature or below.