82207-08-7

Upstream product

• 16807-60-6 3-methoxycyclohex-2-en-1-one 
• 6947-94-0 2-methyl-3-furancarboxylic acid 
• 186581-53-3 diazomethane 
• 82207-07-6 2-(3-Oxo-cyclohex-1-enylmethyl)-furan-3-carboxylic acid 

Downstream Products

• 1856-58-2 (+/-)-dihydrocallitrisin 

Relevant academic research and scientific papers

Total Synthesis of Three Eudesman-12,8-olides, (+/-)-Isoalantolactone, (+/-)-Dihydrocallitrisin and (+/-)-Septuplinolide; Structure Revision of Septuplinolide

Four eudesman-12,8-olides, (+/-)-isoalantolactone, (+/-)-dihydrocallitrisin, (+/-)-septuplinolide and its epimeric eudesmanolide at C-4 were synthesized stereoselectively via the route involving alkylation annulation of 2-methyl-3-furoic acid and oxidation of the furan ring.It was found that the structure of septuplinolide is the C-4 epimer of the reported structure.

TOTAL SYNTHESIS OF (+/-)-ISOALANTOLACTONE AND (+/-)-DIHYDROCALLITRISIN

Two eudesmanolides having opposite stereochemistry of lactone ring each other, (+/-)-isoalantolactone and (+/-)-dihydrocallitrisin were sythesized stereoselectively by a route involving alkylation of 2-methyl-3-furonic acid and oxidation of furan ring.