82209-72-1 Usage
General Description
14-deoxyandrographoside is a chemical compound found in the plant Andrographis paniculata, commonly known as the king of bitters. It is a diterpenoid lactone with potential medicinal properties, including anti-inflammatory, hepatoprotective, and anti-tumor effects. Studies have shown that 14-deoxyandrographoside may have potential therapeutic benefits for various health conditions, such as rheumatoid arthritis, liver diseases, and certain types of cancers. Its biological activities are attributed to its ability to modulate immune responses, reduce oxidative stress, and inhibit key pathways involved in inflammation and tumorigenesis. Further research is needed to fully understand the pharmacological effects and clinical applications of 14-deoxyandrographoside.
Check Digit Verification of cas no
The CAS Registry Mumber 82209-72-1 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,2,2,0 and 9 respectively; the second part has 2 digits, 7 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 82209-72:
(7*8)+(6*2)+(5*2)+(4*0)+(3*9)+(2*7)+(1*2)=121
121 % 10 = 1
So 82209-72-1 is a valid CAS Registry Number.
InChI:InChI=1/C26H40O9/c1-14-4-7-18-25(2,16(14)6-5-15-9-11-33-23(15)32)10-8-19(28)26(18,3)13-34-24-22(31)21(30)20(29)17(12-27)35-24/h9,16-22,24,27-31H,1,4-8,10-13H2,2-3H3/t16?,17-,18+,19-,20-,21+,22-,24-,25+,26+/m1/s1
82209-72-1Relevant articles and documents
Glucosyltransferase Capable of Catalyzing the Last Step in Neoandrographolide Biosynthesis
Li, Yuan,Lin, Hui-Xin,Wang, Jian,Yang, Jian,Lai, Chang-Jiang-Sheng,Wang, Xing,Ma, Bao-Wei,Tang, Jin-Fu,Li, Yong,Li, Xin-Lin,Guo, Juan,Gao, Wei,Huang, Lu-Qi
, p. 5999 - 6002 (2018)
ApUGT, a diterpene glycosyltransferase from Andrographis paniculata, could transfer a glucose to the C-19 hydroxyl moiety of andrograpanin to form neoandrographolide. This glycosyltransferase has a broad substrate scope, and it can glycosylate 26 natural and unnatural compounds of different structural types. This study provides a basis for exploring the glycosylation mechanism of ent-labdane-type diterpenes and plays an important role in diversifying the structures used in drug discovery.
