82212-14-4

Basic information

• Product Name: 2-chloro-5-(1H-tetrazol-5-yl)sulphanilamide
• Synonyms: 2-chloro-5-(1H-tetrazol-5-yl)sulphanilamide;-AMINO-2-CHLORO-5-(1H-TETRAZOLE-5YL)BENZENESULFONAMIDE(U);4-Amino-2-Chloro-5-(1H-Tetrazole-5-yl)Benzenesulfonamide;4-AMINO-2-CHLORO-5-(1 H-TETRAZOLE-5 YL)BENZENESULFONAMIDE (U);4-Amino-2-chloro-5-(1H-tetrazol-5-yl)benzenesulfonamide;5-(2-Amino-4-chloro-5-sulfamoylphenyl)-1H-tetrazole;Einecs 279-922-2;5-(2-Amino-4-chloro-5-sulfamoylphenyl)-1H-tetrazole
• CAS NO: 82212-14-4
• Molecular Formula: C7H7ClN6O2S
• Molecular Weight: 274.68748
• EINECS: 279-922-2
• Mol File: 82212-14-4.mol

Chemical Properties

• Boiling Point: 633.871 °C at 760 mmHg
• Flash Point: 337.153 °C
• Appearance: /
• Density: 1.762 g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.691
• Storage Temp.: Keep in dark place,Sealed in dry,Room Temperature
• Solubility: soluble in Dimethylformamide
• PKA: 3.40±0.10(Predicted)
• CAS DataBase Reference: 2-chloro-5-(1H-tetrazol-5-yl)sulphanilamide(CAS DataBase Reference)
• NIST Chemistry Reference: 2-chloro-5-(1H-tetrazol-5-yl)sulphanilamide(82212-14-4)
• EPA Substance Registry System: 2-chloro-5-(1H-tetrazol-5-yl)sulphanilamide(82212-14-4)

Safety Data

• Hazardous Substances Data: 82212-14-4(Hazardous Substances Data)

Usage

Uses

Used in Organic Chemistry Research:
2-Chloro-5-(1H-tetrazol-5-yl)sulphanilamide is utilized as a research compound in the field of organic chemistry, particularly for studies focused on the synthesis and properties of complex molecular structures. Its unique combination of functional groups offers opportunities for exploring novel chemical reactions and bonding patterns.
Used in Pharmaceutical Development:
In the pharmaceutical industry, 2-chloro-5-(1H-tetrazol-5-yl)sulphanilamide is employed as a potential lead compound for the development of new drugs. Its bioactivity and structural features make it a candidate for further investigation into its therapeutic potential, including possible applications in the treatment of various diseases.
Used in Material Science:
2-Chloro-5-(1H-tetrazol-5-yl)sulphanilamide may also find applications in material science, where its unique molecular structure could be leveraged to create new materials with specific properties. Researchers may explore its use in the development of advanced materials for applications such as sensors, catalysts, or specialized coatings.

InChI:InChI=1/C7H7ClN6O2S/c8-4-2-5(9)3(7-11-13-14-12-7)1-6(4)17(10,15)16/h1-2H,9H2,(H2,10,15,16)(H,11,12,13,14)

Upstream product

• 34662-32-3 4-chloro-2-nitrobenzonitrile 
• 92567-02-7 C₇H₄ClN₅O₂ 

Relevant articles and documents

Azosemide intermediate synthesizing method

The invention discloses an azosemide intermediate synthesizing method. The method comprises the steps of performing tetrazole reaction to prepare a compound A: warming and enabling 4-chlorin-2-nitro benzonitrile and sodium azide to react under action of a catalyst and extracting reaction liquid by water to obtain reaction liquid of the compound A; directly performing hydrogenation reaction to prepare a compound B; performing chlorosulfonation reaction to prepare a compound C: slowly dropping qualified compound B and chlorosulfonic acid into cold water after temperature reaction and center control qualification, extracting through an organic solvent, standing for layering and decompressing, evaporating and drying the solvent in an organic phase mode to obtain a compound crude product C; performing ammonolysis reaction to prepare a compound D. Compared with the prior art, raw materials of the method disclosed by the invention are easy to obtain and low in cost; the method is low in cost, convenient to operate, suitable for industrialization and little in generated three wastes; furthermore, comprehensive utilization of waste can meet national industrial policy.