82230-83-9Relevant academic research and scientific papers
Synthesis of phosphaguanidines by hydrophosphination of carbodiimides with phosphine boranes
Busacca, Carl A.,Milligan, John A.,Rattanangkool, Eakkaphon,Ramavarapu, Cyrus,Chen, Anji,Saha, Anjan K.,Li, Zhibin,Lee, Heewon,Geib, Steven J.,Wang, Guijun,Senanayake, Chris H.,Wipf, Peter
, p. 9878 - 9887 (2014)
The direct addition of anionic secondary phosphine boranes to carbodiimides yields both chiral and achiral phosphaguanidine boranes under ambient temperature conditions. An analogous preparation of menthol-derived phosphinite boranes is also described. These products can be deborinated to give the corresponding phosphines, and subsequently oxidized to give phosphine oxides. The robustness of this method was further demonstrated in the synthesis of structurally novel cyclic phosphaguanidines. (Chemical Equation Presented).
A New and Efficient Preparation of Cyclic Carbodiimides from Bis(iminophosphoranes) and the System Boc2O/DMAP
Molina, Pedro,Alajarin, Mateo,Sanchez-Andrada, Pilar,Elguero, Jose,Jimeno, Maria Luisa
, p. 7306 - 7315 (2007/10/02)
A one-pot synthesis of cyclic carbodiimides which involves reaction of C,C-bis(aryliminophosphoranes) connected by aliphatic bridges with Boc2O in the presence of DMAP is described.The method is also applicable when a heteroatom such as oxygen or nitrogen is incorporated into the tether connecting the two aromatic rings.A conformation study has been carried out on carbodiimide 23a, which possess a central nine-membered ring, using 1H NMR spectroscopy and semiempirical as well as molecular mechanics calculations.
