82238-34-4

Upstream product

• 78602-07-0 (cis)-N,N-diethyl-2,3-dihydro-2-methyl-3-phenyl-2-azetecarboxamide 1-oxide 
• 73227-48-2 (2R,3R)-2-Methyl-1-oxy-3-phenyl-2,3-dihydro-azete-2-carboxylic acid diethylamide 

Downstream Products

• 78602-13-8 Acetic acid (2R,3R)-2-diethylcarbamoyl-2-methyl-4-oxo-3-phenyl-azetidin-1-yl ester 
• 78602-13-8 N,N-diethyl-1-(acetyloxy)-4-methyl-3-phenyl-2-azetidinone-4-carboxamide 
• 78602-11-6 N,N-diethyl-1-hydroxy-4-methyl-3-phenyl-2-azetidinone-4-carboxamide 
• 84109-34-2 N,N-diethyl-4-methyl-3-phenyl-2-azetidinone-4-carboxamide 
• 82238-37-7 (2R,3R)-4-Cyano-2-methyl-1-oxy-3-phenyl-2,3-dihydro-azete-2-carboxylic acid diethylamide 
• 82238-36-6 (2R,3S,4R)-4-Cyano-1-hydroxy-2-methyl-3-phenyl-azetidine-2-carboxylic acid diethylamide 
• 73227-48-2 (2R,3R)-2-Methyl-1-oxy-3-phenyl-2,3-dihydro-azete-2-carboxylic acid diethylamide 

Relevant academic research and scientific papers

Chemistry of Four-Membered Cyclic Nitrones. 4. Reaction with Electrophilic Reagents and Conversion into β-Lactam Derivatives

The conversion of the four-membered cyclic nitrone 1a into a β-lactam has been investigated by using several electrophilic reagents.With methanesulfonyl chloride or with acetic acid, 1a reacts to give the oxime 2.In acetic acid this oxime undergoes cycliz

OXIDATION OF N-HYDROXYAZETIDINES: A NOVEL SYNTHESIS OF N-ACETOXY β-LACTAMS AND FOUR-MEMBERED CYCLIC NITRONES

The N-hydroxyazetidines 2 and 3 are prepared starting from 2,3-dihydroazete 1-oxides (1a and 1b) by reduction with sodium borohydride and by reaction with a nucleophile, respectively.The N-hydroxyazetidines 2 and 3 can be oxidized with mercury(II)oxide to