82239-20-1 Usage
General Description
2,3-Dichlorophenyl-4-nitrophenyl ether is a chemical compound that is commonly used as an intermediate in the synthesis of pharmaceuticals and agrochemicals. It is a yellow crystalline solid that is insoluble in water but soluble in organic solvents. The compound is stable under normal conditions, but may react violently with strong oxidizing agents. It is also a potential mutagen and has been shown to cause skin irritation and serious eye damage in laboratory studies. Additionally, it is considered to be harmful to aquatic life and may cause long-term adverse effects in the aquatic environment. Therefore, proper handling and disposal of 2,3-dichlorophenyl-4-nitrophenyl ether is necessary to prevent harm to humans and the environment.
Check Digit Verification of cas no
The CAS Registry Mumber 82239-20-1 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,2,2,3 and 9 respectively; the second part has 2 digits, 2 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 82239-20:
(7*8)+(6*2)+(5*2)+(4*3)+(3*9)+(2*2)+(1*0)=121
121 % 10 = 1
So 82239-20-1 is a valid CAS Registry Number.
InChI:InChI=1/C12H7Cl2NO3/c13-10-2-1-3-11(12(10)14)18-9-6-4-8(5-7-9)15(16)17/h1-7H
82239-20-1Relevant articles and documents
Synthesis and biological activity of 2-(trifluoromethyl)-1H-benzimidazole derivatives against some protozoa and Trichinella spiralis
Hernández-Luis, Francisco,Hernández-Campos, Alicia,Castillo, Rafael,Navarrete-Vázquez, Gabriel,Soria-Arteche, Olivia,Hernández-Hernández, Manuel,Yépez-Mulia, Lilián
experimental part, p. 3135 - 3141 (2010/09/03)
A series of 2-(trifluoromethyl)-1H-benzimidazole derivatives (1ae1i) were synthesized via Phillips cyclocondensation of a substituted 1,2-phenylenediamine and trifluoroacetic acid. The synthesized compounds were evaluated in vitro against various protozoan parasites: Giardia intestinalis, Entamoeba histolytica, Trichomonas vaginalis and Leishmania mexicana, and they showed nanomolar activities against the first three protozoa tested. The compounds were also tested in vitro and in vivo against the nematode Trichinella spiralis. Compounds 1b, 1c and 1e had the most desirable in vitro antiparasitic profile against all parasites studied. In the in vivo model against T. spiralis, compounds 1b and 1e showed good activity against the adult phase at 75 mg/Kg. However, against the muscle larvae stage, only compound 1f exhibited in vivo antiparasitic efficacy.
