82250-54-2

Basic information

• Product Name: 5-Chloro-2-methoxy-benzoyl isocyanate
• Synonyms: 5-Chloro-2-methoxy-benzoyl isocyanate
• CAS NO: 82250-54-2
• Molecular Weight: 211.605
• Mol File: 82250-54-2.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 5-Chloro-2-methoxy-benzoyl isocyanate(CAS DataBase Reference)
• NIST Chemistry Reference: 5-Chloro-2-methoxy-benzoyl isocyanate(82250-54-2)
• EPA Substance Registry System: 5-Chloro-2-methoxy-benzoyl isocyanate(82250-54-2)

Safety Data

• Hazardous Substances Data: 82250-54-2(Hazardous Substances Data)

Upstream product

• 79-37-8 oxalyl dichloride 
• 23068-80-6 5-chloro-2-methoxybenzamide 

Downstream Products

• 139632-35-2 1-(5-Chloro-2-methoxy-benzoyl)-3-((1R,3R,5S)-8-methyl-8-aza-bicyclo[3.2.1]oct-3-yl)-urea 

Relevant articles and documents

Investigation of novel pesticides with insecticidal and antifungal activities: Design, synthesis and SAR studies of benzoylpyrimidinylurea derivatives

In order to find pesticides with insecticidal and antifungal activities, a series of novel benzoyl pyrimidinylurea derivatives were designed and synthesized. All target compounds were identified by 1H-NMR spectroscopy and HRMS. Insecticidal and antifungal activity of these compounds were evaluated and the structure-activity relationships (SAR) were clearly and comprehensively illustrated. Compound 7, with low toxicity to zebrafish (LC50 = 378.387 μg mL?1) showed 100% inhibition against mosquito (Culex pipiens pallens) at 0.25 μg mL?1. Both compounds 19 and 25 exhibited broad-spectrum fungicidal activity (>50% inhibitory activities against 13 phytopathogenic fungi), which were better than those of the commercial pesticide pyrimethanil (>50% inhibitory activities against eight phytopathogenic fungi). Furthermore, compounds 19 and 25 exhibited protective activity against Sclerotinia sclerotiorum on leaves of Brassica oleracea L. during in vivo experiments.