82257-45-2

Upstream product

• 38858-74-1 (bicyclo[4.1.0]heptan-1-yloxy)trimethylsilane 
• 78-94-4 methyl vinyl ketone 
• 200860-67-9 6-(4-oxopentyl)-1,4-dioxaspiro[4.5]decane 
• 93-59-4 Perbenzoic acid 
• 200860-45-3 6-(3-Phenylsulfanyl-propyl)-1,4-dioxa-spiro[4.5]decane 
• 77516-33-7 2-(3-Phenylsulfanyl-propyl)-cyclohexanone 
• 94-66-6 2-allylcyclohexan-1-one 

Relevant academic research and scientific papers

Preparation of aliphatic ketones through a ruthenium-catalyzed tandem cross-metathesis/allylic alcohol isomerization

Grubbs' 2nd generation and Hoveyda-Grubbs' ruthenium alkylidenes are shown to be effective catalysts for cross-metatheses of allylic alcohols with cyclic and acyclic olefins, as well as isomerization of the resulting allylic alcohols to alkyl ketones. The net result of this new tandem methodology is a single-flask process that provides highly functionalized, ketone-containing products from simple allylic alcohol precursors.

The preparation of synthetically useful carbonyl-protected δ- and ε-lithio ketones via reductive lithiation

The aromatic radical-anion induced reductive lithiation of the acetals or thioacetals of δ- and ε-(phenylthio)ketones provides δ- and ε-lithioketone equivalents. Primary and tertiary organolithiums have been generated and the ketone function may be part o

SYNTHESIS OF 1,6-HETEROSUBSTITUTED PRODUCTS VIA RADICALS

Ketones and electron deficient alkenes are combined with each other via a methylene group to yield 1,6-heterosubstituted products in a radical chain reaction.