82260-53-5

Upstream product

• 82260-55-7 (3R,4S)-1-<2-(4-benzyloxy-3-methyloxyphenyl)-2-hydroxyethyl>-3-ethyl-4-piperidineacetic acid ethyl ester 
• 1835-12-7 3-methoxy-4-benzyloxy-α-bromoacetophenone 
• 82260-54-6 (3R,4S)-(+)-1-(4-benzyloxy-3-methoxyphenacyl)-3-ethyl-4-piperidineacetic acid ethyl ester 
• 56246-53-8 (+)-ethyl cincholoiponate 

Relevant academic research and scientific papers

Quinolizidines. XII. Synthetic Incorporation of Ethyl Cincholoiponate into a Tricyclic Intermediate Adaptable to Chiral Syntheses of the 10-Hydroxy-9-methoxybenzoquinolizidine-Type Alangium Alkaloids

For the purpose of securing a key intermediate for chiral syntheses of the 10-hydroxy-9-methoxybenzoquinolizidine-type Alangium alkaloids (type 4), the tricyclic ester (-)-15 has been synthesized from ethyl cincholoiponate and 4-benzyloxy-3-met

CONVERSION OF ETHYL CINCHOLOIPONATE INTO A TRICYCLIC INTERMEDIATE ADAPTABLE TO CHIRAL SYNTHESES OF 10-DEMETHYLATED ALANGIUM ALKALOIDS

The title (-)-tricyclic amino ester VII has been synthesized by means of an initial condensation of 4-benzyloxy-3-methoxyphenacyl bromide with (+)-ethyl cincholoiponate (VIII), derived from the Cinchona alkaloid cinchonine, and succeeding steps proceeding